Antimicrobial Properties and Application of Polysaccharides and Their Derivatives

Gui-Xue Xia; Yue-Ming Wu; Yu-Fang Bi; Kang Chen; Wei-Wei Zhang; Shi-Qi Liu; Wen-Jing Zhang; Run-Hui Liu

doi:10.1007/s10118-021-2506-2

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Antimicrobial Properties and Application of Polysaccharides and Their Derivatives

REVIEW | Updated：2020-10-16

- Antimicrobial Properties and Application of Polysaccharides and Their Derivatives
- Chinese Journal of Polymer Science Vol. 39, Issue 2, Pages: 133-146(2021)
- Affiliations：
  
  a.State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China
  b.Frontiers Science Center for Materiobiology and Dynamic Chemistry, Key Laboratory of Specially Functional Polymeric Materials and Related Technology (ECUST) Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
- Author bio：
  
  rliu@ecust.edu.cn
- Funds：
- DOI：10.1007/s10118-021-2506-2
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Gui-Xue Xia, Yue-Ming Wu, Yu-Fang Bi, et al. Antimicrobial Properties and Application of Polysaccharides and Their Derivatives. [J]. Chinese Journal of Polymer Science 39(2):133-146(2021)
DOI：

Gui-Xue Xia, Yue-Ming Wu, Yu-Fang Bi, et al. Antimicrobial Properties and Application of Polysaccharides and Their Derivatives. [J]. Chinese Journal of Polymer Science 39(2):133-146(2021) DOI： 10.1007/s10118-021-2506-2.

摘要

Abstract

With the quick emergence of antibiotic resistance and multi-drug resistant microbes, more and more attention has been paid to the development of new antimicrobial agents that have potential to take the challenge. Polysaccharides, as one of the major classes of biopolymers, were explored for their antimicrobial properties and applications, owing to their easy accessibility, biocompatibility and easy modification. Polysaccharides and their derivatives have variable demonstrations and applications as antimicrobial agents and antimicrobial biomaterials. A variety of polysaccharides, such as chitosan, dextran, hyaluronic acid, cellulose, other plant/animal-derived polysaccharides and their derivatives have been explored for antimicrobial applications. We expect that this review can summarize the important progress of this field and inspire new concepts, which will contribute to the development of novel antimicrobial agents in combating antibiotic resistance and drug-resistant antimicrobial infections.

关键词

Keywords

AntimicrobialDrug resistancePolysaccharidesPolysaccharide derivativesChitosan

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Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province, Department of Engineering Mechanics, Zhejiang University

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State Key Laboratory of Separation Membranes and Membrane Processes, School of Materials Science and Engineering, Tiangong University

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics and University of Chinese Academy of Sciences (UCAS), Chinese Academy of Sciences (CAS)

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