Tough Polymeric Hydrogels Based on Amino Acid Derivative Mediated Dynamic Metal Coordination Bonds

Meng Li; Meng-Yuan Zhang; Wu-Xuan Lei; Zhu-Ting Lv; Qing-Hua Shang; Zheng Zhao; Jiang-Tao Li; Yi-Long Cheng

doi:10.1007/s10118-024-3177-6

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Tough Polymeric Hydrogels Based on Amino Acid Derivative Mediated Dynamic Metal Coordination Bonds

RESEARCH ARTICLE | Updated：2024-09-23

- Tough Polymeric Hydrogels Based on Amino Acid Derivative Mediated Dynamic Metal Coordination Bonds
- Tough Polymeric Hydrogels Based on Amino Acid Derivative Mediated Dynamic Metal Coordination Bonds
- 高分子科学（英文版） 2024年42卷第10期页码：1578-1588
- Affiliations：
  
  a.Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, School of Chemistry, Xi’an Jiaotong University, Xi’an 710049, China
  b.Polymer Materials & Engineering Department School of Materials Science & Engineering Chang’an University, Xi’an 710064, China
  c.School of Electrical Engineering, Xi’an Jiaotong University, Xi’an 710049, China
  d.Department of Nuclear Medicine, the First Affiliated Hospital of China, Xi’an Jiaotong University, Xi’an 710049, China
- Author bio：
  
  yilongcheng@mail.xjtu.edu.cn
- Funds：
  
  This work was financially supported by the National Natural Science Foundation of China (Nos. 52322309 and 52173139), the “Young Talent Support Plan” of Xi’an Jiaotong University, and Fundamental Research Funds for the Central Universities (No. xzy022023018).;Electronic supplementary information (ESI) is available free of charge in the online version of this article at http://doi.org/10.1007/s10118-024-3177-6.
- DOI：10.1007/s10118-024-3177-6
  中图分类号：
- 纸质出版日期：2024-10-01，
  
  网络出版日期：2024-08-28，
  
  收稿日期：2024-05-11，
  
  修回日期：2024-06-02，
  
  录用日期：2024-06-03
- Accepted：
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Li, M.; Zhang, M. Y.; Lei, W. X.; Lv, Z. T.; Shang, Q. H.; Zhao, Z.; Li, J. T.; Cheng, Y. L. Tough polymeric hydrogels based on amino acid derivative mediated dynamic metal coordination bonds. Chinese J. Polym. Sci. 2024, 42, 1578–1588

Meng Li, Meng-Yuan Zhang, Wu-Xuan Lei, et al. Tough Polymeric Hydrogels Based on Amino Acid Derivative Mediated Dynamic Metal Coordination Bonds[J]. Chinese Journal of Polymer Science, 2024,42(10):1578-1588.
Li, M.; Zhang, M. Y.; Lei, W. X.; Lv, Z. T.; Shang, Q. H.; Zhao, Z.; Li, J. T.; Cheng, Y. L. Tough polymeric hydrogels based on amino acid derivative mediated dynamic metal coordination bonds. Chinese J. Polym. Sci. 2024, 42, 1578–1588 DOI： 10.1007/s10118-024-3177-6.

Meng Li, Meng-Yuan Zhang, Wu-Xuan Lei, et al. Tough Polymeric Hydrogels Based on Amino Acid Derivative Mediated Dynamic Metal Coordination Bonds[J]. Chinese Journal of Polymer Science, 2024,42(10):1578-1588. DOI： 10.1007/s10118-024-3177-6.

摘要

This study reported the preparation of tough polymer hydrogels through Zr

coordination. Compared to AAla without hydroxyl groups

copolymerization of ASer with AM in water followed by incubation with ZrOCl

solution significantly improved the comprehensive mechanical properties of the hydrogels and demonstrated great potential for applications in flexible sensors.

Abstract

The development of physically crosslinked hydrogels with excellent mechanical and sensing properties is of importance for expanding the practical applications of intelligent soft hydrogel materials. Herein

after copolymerization of hydroxyl-containing amino acid derivative N-acryloyl serine (ASer) with acrylamide (AM)

we introduce Zr

through an immersion strategy to construct metal ion-toughened non-covalent crosslinked hydrogels (with tensile strength of up to 5.73 MPa). It is found that the synergistic coordination of hydroxyl and carboxyl groups with Zr

substantially increases the crosslinking density of the hydrogels

thereby imparting markedly superior mechanical properties compared to hydroxyl-free Zr

-crosslinked hydrogels

such as N-acryloyl alanine (AAla) copolymerized with AM hydrogels (with tensile strength of 2.98 MPa). Through the adjustment of the composition of the copolymer and

the density of coordination bonds

the mechanical properties of the hydrogels can be modulated over a wide range. Additionally

due to the introduction of metal ions and the dynamic nature of coordination bonds

the hydrogels also exhibit excellent sensing performance and good self-recovery properties

paving the way for the development of flexible electronic substrates with outstanding comprehensive performances.

关键词

Keywords

HydrogelAmino acidMetal coordinationMechanical performanceFlexible sensor

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