Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes

Zhan Li; Haotian Li; Jianhua Zhang; Xianhu Liu; Zhipeng Gu; Yiwen Li

doi:10.1007/s10118-020-2486-7

Your Location：

Home >

Browse articles >

Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes

RAPID COMMUNICATION | Updated：2020-08-25

- Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes
- Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes
- Chinese Journal of Polymer Science 2020年38卷第11期页码：1149-1156
- Affiliations：
  
  a.College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China
  b.School of Materials Science and Engineering, Xihua University, Chengdu 610039, China
  c.National Engineering Research Center for Advanced Polymer Processing Technology, Zhengzhou University, Zhengzhou 450002, China
- Author bio：
  
  guzhipeng2019@scu.edu.cn (Z.G.)
  ywli@scu.edu.cn (Y.L.)
- Funds：
  
  This work was financially supported by the National Natural Science Foundation of China (Nos. 51603133 and 21774079), National Key R&D Program of China (No. 2019YFA0904500), the Program of the Science, Technology Department of Guangzhou, China (No. 201803020039), and the Fundamental Research Funds for Central Universities.
- DOI：10.1007/s10118-020-2486-7
  中图分类号：
- 收稿：2020-07-11，
  
  修回：2020-7-26，
  
  录用：2020-7-27，
  
  网络首发：2020-08-25，
  
  纸质出版：2020-08-14
- Accepted：
Scan QR Code
Li, Z.; Li, H.; Zhang, J.; Liu, X.; Gu, Z.; Li, Y. Ultrasmall nanoparticle ROS scavengers based on polyhedral oligomeric silsesquioxanes. Chinese J. Polym. Sci. 2020, 38, 1149–1156

Zhan Li, Haotian Li, Jianhua Zhang, et al. Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes[J]. Chinese Journal of Polymer Science, 2020, 38(11): 1149-1156.
Li, Z.; Li, H.; Zhang, J.; Liu, X.; Gu, Z.; Li, Y. Ultrasmall nanoparticle ROS scavengers based on polyhedral oligomeric silsesquioxanes. Chinese J. Polym. Sci. 2020, 38, 1149–1156 DOI： 10.1007/s10118-020-2486-7.

Zhan Li, Haotian Li, Jianhua Zhang, et al. Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes[J]. Chinese Journal of Polymer Science, 2020, 38(11): 1149-1156. DOI： 10.1007/s10118-020-2486-7.

摘要

Abstract

Although tremendous efforts have been devoted to the structural and functional tailoring of natural polyphenol-functionalized nanoparticles

preparing ultrasmall sized (

6 nm) particles with precisely-defined structures has remained a grand challenge. In this work

we reported the preparation of ultra-small and precisely structured polyhedral oligomeric silsesquioxanes (POSS)-based polyphenol nanoparticles (T

and T

-GAPOSS) by accurately functionalizing the POSS surface with plant polyphenol gallic acid units

via

thiol-Michael “click” reactions. Those polyphenol nanoparticles exhibited strong free radical scavenging capacity

good biocompatibility and ability to resist cell oxidative damage

which demonstrated great potentials in inhibiting oxidative stress induced pathologies.

关键词

Keywords

references

Cairns, R. A.; Harris, I. S.; Mak, T. W. . Regulation of cancer cell metabolism . Nat. Rev. Cancer. , 2011 . 11 85 DOI: 10.1038/nrc2981 http://doi.org/10.1038/nrc2981 .

Jiao, X.; Li, Y.; Niu, J.; Xie, X.; Wang, X.; Tang, B. . Small-molecule fluorescent probes for imaging and detection of reactive oxygen, nitrogen, and sulfur species in biological systems . Anal. Chem. , 2017 . 90 533 - 555 . .

Zhang, J.; Fu, Y.; Yang, P.; Liu, X.; Li, Y.; Gu, Z. . ROS scavenging biopolymers for anti-inflammatory diseases: classification and formulation . Adv. Mater. Interfaces , 2020 . 64 2000632 .

Wang, C.; Sang, H.; Wang, Y.; Zhu, F.; Hu, X.; Wang, X.; Wang, X.; Li, Y.; Cheng, Y. . Foe to friend: supramolecular nanomedicines consisting of natural polyphenols and bortezomib . Nano Lett. , 2018 . 18 7045 - 7051 . DOI: 10.1021/acs.nanolett.8b03015 http://doi.org/10.1021/acs.nanolett.8b03015 .

Rahim, M. A.; Kristufek, S. L.; Pan, S.; Richardson, J. J.; Caruso, F. . Phenolic building blocks for the assembly of functional materials . Angew. Chem. Int. Ed. , 2019 . 58 1904 - 1927 . DOI: 10.1002/anie.201807804 http://doi.org/10.1002/anie.201807804 .

Dai, Q.; Geng, H.; Yu, Q.; Hao, J.; Cui, J. . Polyphenol-based particles for theranostics . Theranostics , 2019 . 9 3170 DOI: 10.7150/thno.31847 http://doi.org/10.7150/thno.31847 .

Shin, M.; Park, E.; Lee, H. . Plant-inspired pyrogallol-containing functional materials . Adv. Funct. Mater. , 2019 . 29 1903022 DOI: 10.1002/adfm.201903022 http://doi.org/10.1002/adfm.201903022 .

Li, M.; Wang, H.; Hu, J.; Hu, J.; Zhang, S.; Yang, Z.; Li, Y.; Cheng, Y. . Smart hydrogels with antibacterial properties built from all natural building blocks . Chem. Mater. , 2019 . 31 7678 - 7685 . DOI: 10.1021/acs.chemmater.9b02547 http://doi.org/10.1021/acs.chemmater.9b02547 .

Yang, P.; Zhang, S.; Chen, X.; Liu, X.; Wang, Z.; Li, Y. . Recent developments in polydopamine fluorescent nanomaterials . Mater. Horiz. , 2020 . 7 746 - 761 . DOI: 10.1039/C9MH01197H http://doi.org/10.1039/C9MH01197H .

Wang, X.; Yang, L.; Yang, P.; Guo, W.; Zhang, Q.; Liu, X.; Li, Y . Metal ions-promoted fabrication of melanin-like poly(L-DOPA) nanoparticles for photothermal actuation . Sci. China Chem. , 2020 . 63 1295 - 1305 . DOI: 10.1007/s11426-020-9797-3 http://doi.org/10.1007/s11426-020-9797-3 .

Shi, X.; Yang, P.; Peng, X.; Huang, C.; Qian, Q.; Wang, B.; He, J.; Liu, X.; Li, Y.; Kuang, T. . Bi-phase fire-resistant polyethylenimine/graphene oxide/melanin coatings using layer by layer assembly technique: smoke suppression and thermal stability of flexible polyurethane foams . Polymer , 2019 . 170 65 - 75 . DOI: 10.1016/j.polymer.2019.03.008 http://doi.org/10.1016/j.polymer.2019.03.008 .

Valgimigli, L.; Baschieri, A.; Amorati, R. . Antioxidant activity of nanomaterials . J. Mater. Chem. B , 2018 . 6 2036 - 2051 . DOI: 10.1039/C8TB00107C http://doi.org/10.1039/C8TB00107C .

Hsieh, D. S.; Wang, H.; Tan, S. W.; Huang, Y. H.; Tsai, C. Y.; Yeh, M. K.; Wu, C. J. . The treatment of bladder cancer in a mouse model by epigallocatechin-3-gallate-gold nanoparticles . Biomaterials , 2011 . 32 7633 - 7640 . DOI: 10.1016/j.biomaterials.2011.06.073 http://doi.org/10.1016/j.biomaterials.2011.06.073 .

Lin, Y. H.; Chen, Z. R.; Lai, C. H.; Hsieh, C. H.; Feng, C. L. . Active targeted nanoparticles for oral administration of gastric cancer therapy . Biomacromolecules , 2015 . 16 3021 - 3032 . DOI: 10.1021/acs.biomac.5b00907 http://doi.org/10.1021/acs.biomac.5b00907 .

Shutava, T. G.; Balkundi, S. S.; Vangala, P.; Steffan, J. J.; Bigelow, R. L.; Cardelli, J. A.; O’Neal, D. P.; Lvov, Y. M. . Layer-by-layer coated gelatin nanoparticles as a vehicle for delivery of natural polyphenols . ACS Nano , 2009 . 3 1877 - 1885 . DOI: 10.1021/nn900451a http://doi.org/10.1021/nn900451a .

Debnath, K.; Shekhar, S.; Kumar, V.; Jana, N. R.; Jana, N. R. . Efficient inhibition of protein aggregation, disintegration of aggregates, and lowering of cytotoxicity by green tea polyphenol-based self-assembled polymer nanoparticles . ACS Appl. Mater. Interfaces , 2016 . 8 20309 - 20318 . DOI: 10.1021/acsami.6b06853 http://doi.org/10.1021/acsami.6b06853 .

Xiang, S.; Yang, P.; Guo, H.; Zhang, S.; Zhang, X.; Zhu, F.; Li, Y. . Green tea makes polyphenol nanoparticles with radical-scavenging activities . Macromol. Rapid Commun. , 2017 . 38 1700446 DOI: 10.1002/marc.201700446 http://doi.org/10.1002/marc.201700446 .

Hu, K.; Miao, L.; Goodwin, T. J.; Li, J.; Liu, Q.; Huang, L. . Quercetin remodels the tumor microenvironment to improve the permeation, retention, and antitumor effects of nanoparticles . ACS Nano , 2017 . 11 4916 - 4925 . DOI: 10.1021/acsnano.7b01522 http://doi.org/10.1021/acsnano.7b01522 .

Ju, K.-Y.; Lee, Y.; Lee, S.; Park, S. B.; Lee, J. K. . Bioinspired polymerization of dopamine to generate melanin-like nanoparticles having an excellent free-radical-scavenging property . Biomacromolecules , 2011 . 12 625 - 632 . DOI: 10.1021/bm101281b http://doi.org/10.1021/bm101281b .

Wang, X.; Chen, Z.; Yang, P.; Hu, J.; Wang, Z.; Li, Y. . Size control synthesis of melanin-like polydopamine nanoparticles by tuning radicals . Polym. Chem. , 2019 . 10 4194 - 4200 . DOI: 10.1039/C9PY00517J http://doi.org/10.1039/C9PY00517J .

Cordes, D. B.; Lickiss, P. D.; Rataboul, F. . Recent developments in the chemistry of cubic polyhedral oligosilsesquioxanes . Chem. Rev. , 2010 . 110 2081 - 2173 . DOI: 10.1021/cr900201r http://doi.org/10.1021/cr900201r .

Li, Z.; Kong, J.; Wang, F.; He, C. . Polyhedral oligomeric silsesquioxanes (POSSs): an important building block for organic optoelectronic materials . J. Mater. Chem. C , 2017 . 5 5283 - 5298 . .

Hou, H.; Li, J.; Li, X.; Forth, J.; Yin, J.; Jiang, X.; Helms, B. A.; Russell, T. P. . Interfacial activity of amine-functionalized polyhedral oligomeric silsesquioxanes (POSS): a simple strategy to structure liquids . Angew. Chem. Int. Ed. , 2019 . 131 10248 - 10253 . DOI: 10.1002/ange.201903420 http://doi.org/10.1002/ange.201903420 .

Li, Z.; Hu, J.; Yang, L.; Zhang, X.; Liu, X.; Wang, Z.; Li, Y. . Integrated POSS-dendrimer nanohybrid materials: current status and future perspective . Nanoscale , 2020 . 12 11395 - 11415 . DOI: 10.1039/D0NR02394A http://doi.org/10.1039/D0NR02394A .

Su, Z.; Zhang, R.; Yan, X.; Guo, Q.; Huang, J.; Shan, W.; Liu, Y.; Liu, T.; Huang, M.; Cheng, S. Z. . The role of architectural engineering in macromolecular self-assemblies via non-covalent interactions: a molecular LEGO approach . Prog. Polym. Sci. , 2020 . 103 101230 DOI: 10.1016/j.progpolymsci.2020.101230 http://doi.org/10.1016/j.progpolymsci.2020.101230 .

Li, Z.; Fu, Y.; Li, Z.; Nan, N.; Zhu, Y.; Li, Y. . Froth flotation giant surfactants . Polymer , 2019 . 162 58 - 62 . DOI: 10.1016/j.polymer.2018.12.023 http://doi.org/10.1016/j.polymer.2018.12.023 .

Zhou, K.; Bisoyi, H. K.; Jin, J. Q.; Yuan, C. L.; Liu, Z.; Shen, D.; Lu, Y. Q.; Zheng, Z. G.; Zhang, W.; Li, Q. . Light-driven reversible transformation between self-organized simple cubic lattice and helical superstructure enabled by a molecular switch functionalized nanocage . Adv. Mater. , 2018 . 30 1800237 DOI: 10.1002/adma.201800237 http://doi.org/10.1002/adma.201800237 .

Kuo, S. W.; Chang, F. C. . POSS related polymer nanocomposites . Prog. Polym. Sci. , 2011 . 36 1649 - 1696 . DOI: 10.1016/j.progpolymsci.2011.05.002 http://doi.org/10.1016/j.progpolymsci.2011.05.002 .

Jeon, J. H.; Tanaka, K.; Chujo, Y. . Synthesis of sulfonic acid-containing POSS and its filler effects for enhancing thermal stabilities and lowering melting temperatures of ionic liquids . J. Mater. Chem. A , 2014 . 2 624 - 630 . DOI: 10.1039/C3TA14039C http://doi.org/10.1039/C3TA14039C .

Li, Y.; Dong, X. H.; Zou, Y.; Wang, Z.; Yue, K.; Huang, M.; Liu, H.; Feng, X.; Lin, Z.; Zhang, W.; Cheng, S. Z. . Polyhedral oligomeric silsesquioxane meets “click” chemistry: rational design and facile preparation of functional hybrid materials . Polymer , 2017 . 125 303 - 329 . DOI: 10.1016/j.polymer.2017.08.008 http://doi.org/10.1016/j.polymer.2017.08.008 .

Zhang, W.; Müller, A. H. . Architecture, self-assembly and properties of well-defined hybrid polymers based on polyhedral oligomeric silsequioxane (POSS) . Prog. Polym. Sci. , 2013 . 38 1121 - 1162 . DOI: 10.1016/j.progpolymsci.2013.03.002 http://doi.org/10.1016/j.progpolymsci.2013.03.002 .

Lu, N.; Lu, Y.; Liu, S.; Jin, C.; Fang, S.; Zhou, X.; Li, Z. . Tailor-engineered POSS-based hybrid gels for bone regeneration . Biomacromolecules , 2019 . 20 3485 - 3493 . DOI: 10.1021/acs.biomac.9b00771 http://doi.org/10.1021/acs.biomac.9b00771 .

Su, Z.; Hsu, C. H.; Gong, Z.; Feng, X.; Huang, J.; Zhang, R.; Wang, Y.; Mao, J.; Wesdemiotis, C.; Li, T.; Cheng, S. Z. . Identification of a Frank-Kasper Z phase from shape amphiphile self-assembly . Nat. Chem. , 2019 . 11 899 - 905 . DOI: 10.1038/s41557-019-0330-x http://doi.org/10.1038/s41557-019-0330-x .

Zou, Y.; Zhang, L.; Yang, L.; Zhu, F.; Ding, M.; Lin, F.; Wang, Z.; Li, Y. . “Click” chemistry in polymeric scaffolds: bioactive materials for tissue engineering . J. Control. Release , 2018 . 273 160 - 179 . DOI: 10.1016/j.jconrel.2018.01.023 http://doi.org/10.1016/j.jconrel.2018.01.023 .

Shavandi, A.; Bekhit, A. E. D. A.; Saeedi, P.; Izadifar, Z.; Bekhit, A. A.; Khademhosseini, A. . Polyphenol uses in biomaterials engineering . Biomaterials , 2018 . 167 91 - 106 . DOI: 10.1016/j.biomaterials.2018.03.018 http://doi.org/10.1016/j.biomaterials.2018.03.018 .

Yang, P.; Gu, Z.; Zhu, F.; Li, Y. . Structural and functional tailoring of melanin-like polydopamine radical scavengers . CCS Chem. , 2020 . 2 128 - 138 . DOI: 10.31635/ccschem.020.201900077 http://doi.org/10.31635/ccschem.020.201900077 .

Li, Z.; Wang, T.; Zhu, F.; Wang, Z.; Li, Y. . Bioinspired fluorescent dihydroxyindoles oligomers . Chin. Chem. Lett. , 2020 . 31 783 - 786 . DOI: 10.1016/j.cclet.2019.05.021 http://doi.org/10.1016/j.cclet.2019.05.021 .

Cheng, X.; Li, M.; Wang, H.; Cheng, Y. . All-small-molecule dynamic covalent gels with antibacterial activity by boronate-tannic acid gelation . Chin. Chem. Lett. , 2020 . 31 869 - 874 . DOI: 10.1016/j.cclet.2019.07.013 http://doi.org/10.1016/j.cclet.2019.07.013 .

Li, Z.; Zhang, J.; Fu, Y.; Yang, L.; Zhu, F.; Liu, X.; Gu, Z.; Li, Y. . Antioxidant shape amphiphiles for accelerated wound healing . J. Mater. Chem. B , 2020 . 8 7018 - 7023 . DOI: 10.1039/D0TB00578A http://doi.org/10.1039/D0TB00578A .

Shan, M.; Gong, C.; Li, B.; Wu, G. . A pH, glucose, and dopamine triple-responsive, self-healable adhesive hydrogel formed by phenylborate-catechol complexation . Polym. Chem. , 2017 . 8 2997 - 3005 . DOI: 10.1039/C7PY00519A http://doi.org/10.1039/C7PY00519A .

浏览量

139

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Supramolecular Polymer-Polyphenol Composite Slurries for High-fidelity Microneedle Fabrication via Ambient-temperature Pressing

Ultrasmall Nanoparticles Diluted Chain Entanglement in Polymer Nanocomposites

Simultaneous Improvements of Thermal Stability and Mechanical Properties of Poly(propylene carbonate) via Incorporation of Environmental-friendly Polydopamine

Highly Regio- and trans-Selective Ring-opening Metathesis Polymerization of Chiral Aza-norbornene with a Simple Phenylimido-Tungsten Catalyst

Molecular Segregation and Melt Memory in Dilute Polycaprolactone with Reduced Entanglements