Kinematics of Non-axially Positioned Vesicles through a Pore

Yun-Long Han; Ming-Ming Ding; Rui Li; Tong-Fei Shi

doi:10.1007/s10118-020-2375-0

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Kinematics of Non-axially Positioned Vesicles through a Pore

ARTICLE | Updated：2019-12-31

- Kinematics of Non-axially Positioned Vesicles through a Pore
- Kinematics of Non-axially Positioned Vesicles through a Pore
- Chinese Journal of Polymer Science 2020年38卷第7期页码：776-783
- Affiliations：
  
  a.School of Materials Science and Engineering, Changchun University of Science and Technology, Changchun 130022, China
  b.State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
  c.School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei 230026, China
- Author bio：
  
  mmding@ciac.ac.cn (M.M.D.)
  lirui@cust.edu.cn (R.L.)
  tfshi@ciac.ac.cn (T.F.S.)
- Funds：
  
  This work was financially supported by the National Natural Science Foundation of China (No. 21604086), Jilin Provincial science and technology development program (No. 20190103124JH), and Key Research Program of Frontier Sciences, CAS (No. QYZDY-SSW-SLH027).
- DOI：10.1007/s10118-020-2375-0
  中图分类号：
- 收稿：2019-10-28，
  
  修回：2019-11-18，
  
  录用：2019-11-25，
  
  网络首发：2019-12-31，
  
  纸质出版：2020-07
- Accepted：
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Han, Y. L.; Ding, M. M.; Li, R.; Shi, T. F. Kinematics of non-axially positioned vesicles through a pore. Chinese J. Polym. Sci. 2020, 38, 776–783

Yun-Long Han, Ming-Ming Ding, Rui Li, et al. Kinematics of Non-axially Positioned Vesicles through a Pore[J]. Chinese Journal of Polymer Science, 2020, 38(7): 776-783.
Han, Y. L.; Ding, M. M.; Li, R.; Shi, T. F. Kinematics of non-axially positioned vesicles through a pore. Chinese J. Polym. Sci. 2020, 38, 776–783 DOI： 10.1007/s10118-020-2375-0.

Yun-Long Han, Ming-Ming Ding, Rui Li, et al. Kinematics of Non-axially Positioned Vesicles through a Pore[J]. Chinese Journal of Polymer Science, 2020, 38(7): 776-783. DOI： 10.1007/s10118-020-2375-0.

摘要

Abstract

We employ finite element method to investigate the kinematics of non-axially positioned vesicles through a pore. To complete the coupling between fluid flow and the vesicle membranes

we use the fluid structure interactions with the arbitrary Lagrangian Eulerian method. Our results demonstrate that the vesicles show different deformations in migration process

in turn an oblique ellipse-shape

slipper-shape

oval-shape. We find that the rotation angle of non-axially positioned vesicles mainly shows the trend of increase

besides the small fluctuation induced by deformation relaxation. Moreover

when the vesicles move towards the axis of the channel

the rotation angle exhibits a decrease because of the decrease of the shear force. However

rotation of axially positioned vesicles hardly occur due to symmetrical shear force. Our results further indicate that the rotation is faster nearby the pore for non-axially positioned vesicles. Our work answers the mapping between the positions of vesicles and deformed states

as well as the change of rotation angle and rotation velocity

which can provide helpful information on the utilization of vesicles in pharmaceutical

chemical

and physiological processes.

关键词

Keywords

references

Guo, X.; Szoka, F. C. . Chemical approaches to triggerable lipid vesicles for drug and gene delivery . Acc. Chem. Res. , 2003 . 36 335 - 341 . DOI: 10.1021/ar9703241 http://doi.org/10.1021/ar9703241 .

Liu, Z. H.; Zhang, Z. Y.; Zhou, C. R.; Jiao, Y. P. . Hydrophobic modifications of cationic polymers for gene delivery . Prog. Polym. Sci. , 2010 . 35 1144 - 1162 . DOI: 10.1016/j.progpolymsci.2010.04.007 http://doi.org/10.1016/j.progpolymsci.2010.04.007 .

Takemoto, H.; Ishii, A.; Miyata, K.; Nakanishi, M.; Oba, M.; Ishii, T.; Yamasaki, Y.; Nishiyama, N.; Kataoka, K. . Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system . Biomaterials , 2010 . 31 8097 - 8105 . DOI: 10.1016/j.biomaterials.2010.07.015 http://doi.org/10.1016/j.biomaterials.2010.07.015 .

Du, J. Z.; Fan, L.; Liu, Q. M. . pH-sensitive block copolymer vesicles with variable trigger points for drug delivery . Macromolecules , 2012 . 45 8275 - 8283 . DOI: 10.1021/ma3015728 http://doi.org/10.1021/ma3015728 .

Gratieri, T.; Alberti, I.; Lapteva, M.; Kalia, Y. N. . Next generation intra- and transdermal therapeutic systems: using non- and minimally-invasive technologies to increase drug delivery into and across the skin . Eur. J. Pharm. Sci. , 2013 . 50 609 - 622 . DOI: 10.1016/j.ejps.2013.03.019 http://doi.org/10.1016/j.ejps.2013.03.019 .

Gambhire, P.; Atwell, S.; Iss, C.; Bedu, F.; Ozerov, I.; Badens, C.; Helfer, E.; Viallat, A.; Charrier, A. . High aspect ratio sub-micrometer channels using wet etching: application to the dynamics of red blood cell transiting through biomimetic splenic slits . Small , 2017 . 13 11 .

Mebius, R. E.; Kraal, G. . Structure and function of the spleen . Nat. Rev. Immunol. , 2005 . 5 606 - 616 . DOI: 10.1038/nri1669 http://doi.org/10.1038/nri1669 .

Popel, A. S.; Johnson, P. C. . Microcirculation and hemorheology . Annu. Rev. Fluid Mech. , 2005 . 37 43 - 69 . DOI: 10.1146/annurev.fluid.37.042604.133933 http://doi.org/10.1146/annurev.fluid.37.042604.133933 .

Zhu, Q.; Salehyar, S.; Cabrales, P.; Asaro, R. J. . Prospects for human erythrocyte skeleton-bilayer dissociation during splenic flow . Biophys. J. , 2017 . 113 900 - 912 . DOI: 10.1016/j.bpj.2017.05.052 http://doi.org/10.1016/j.bpj.2017.05.052 .

Barthes-Biesel, D. . Motion and deformation of elastic capsules and vesicles in flow . Annu. Rev. Fluid Mech. , 2016 . 48 25 - 52 . DOI: 10.1146/annurev-fluid-122414-034345 http://doi.org/10.1146/annurev-fluid-122414-034345 .

Chang, K. S.; Olbricht, W. L. . Experimental studies of the deformation and breakup of a synthetic capsule in steady and unsteady simple shear-flow . J. Fluid Mech. , 1993 . 250 609 - 633 . DOI: 10.1017/S0022112093001582 http://doi.org/10.1017/S0022112093001582 .

de, Loubens C.; Deschamps, J.; Georgelin, M.; Charrier, A.; Edwards-Levy, F.; Leonetti, M. . Mechanical characterization of cross-linked serum albumin microcapsules . Soft Matter , 2014 . 10 4561 - 4568 . DOI: 10.1039/c4sm00349g http://doi.org/10.1039/c4sm00349g .

Koleva, I.; Rehage, H. . Deformation and orientation dynamics of polysiloxane microcapsules in linear shear flow . Soft Matter , 2012 . 8 3681 - 3693 . DOI: 10.1039/c2sm07182g http://doi.org/10.1039/c2sm07182g .

Villone, M. M.; Greco, F.; Hulsen, M. A.; Maffettone, P. L. . Simulations of an elastic particle in Newtonian and viscoelastic fluids subjected to confined shear flow . J. Non-Newton. Fluid Mech. , 2014 . 210 47 - 55 . DOI: 10.1016/j.jnnfm.2014.05.003 http://doi.org/10.1016/j.jnnfm.2014.05.003 .

Villone, M. M.; Greco, F.; Hulsen, M. A.; Maffettone, P. L. . Numerical simulations of deformable particle lateral migration in tube flow of Newtonian and viscoelastic media . J. Non-Newton. Fluid Mech. , 2016 . 234 105 - 113 . DOI: 10.1016/j.jnnfm.2016.05.006 http://doi.org/10.1016/j.jnnfm.2016.05.006 .

Walter, A.; Rehage, H.; Leonhard, H. . Shear-induced deformations of polyamide microcapsules . Colloid Polym. Sci. , 2000 . 278 169 - 175 . DOI: 10.1007/s003960050028 http://doi.org/10.1007/s003960050028 .

Fournier, J. B.; Galatola, P. . Corrections to the Laplace law for vesicle aspiration in micropipettes and other confined geometries . Soft Matter , 2008 . 4 2463 - 2470 . DOI: 10.1039/b806589f http://doi.org/10.1039/b806589f .

Gompper, G.; Kroll, D. M. . Driven transport of fluid vesicles through narrow pores . Phys. Rev. E , 1995 . 52 4198 - 4208 . .

Han, Y. L.; Lin, H.; Ding, M. M.; Li, R.; Shi, T. F. . Flow-induced translocation of vesicles through a narrow pore . Soft Matter , 2019 . 15 3307 - 3314 . DOI: 10.1039/C9SM00116F http://doi.org/10.1039/C9SM00116F .

Khunpetch, P.; Man, X. K.; Kawakatsu, T.; Doi, M. . Translocation of a vesicle through a narrow hole across a membrane . J. Chem. Phys. , 2018 . 148 7 .

Linke, G. T.; Lipowsky, R.; Gruhn, T. . Osmotically induced passage of vesicles through narrow pores . Europhys. Lett. , 2006 . 74 916 - 922 . DOI: 10.1209/epl/i2005-10585-0 http://doi.org/10.1209/epl/i2005-10585-0 .

Park, S. Y.; Dimitrakopoulos, P. . Transient dynamics of an elastic capsule in a microfluidic constriction . Soft Matter , 2013 . 9 8844 - 8855 . DOI: 10.1039/c3sm51516h http://doi.org/10.1039/c3sm51516h .

Shojaei, H. R.; Muthukumar, M. . Translocation of an incompressible vesicle through a pore . J. Phys. Chem. B , 2016 . 120 6102 - 6109 . DOI: 10.1021/acs.jpcb.6b02079 http://doi.org/10.1021/acs.jpcb.6b02079 .

Tordeux, C.; Fournier, J. B. . Extravasation of adhering vesicles . Europhys. Lett. , 2002 . 60 875 - 881 . DOI: 10.1209/epl/i2002-00299-3 http://doi.org/10.1209/epl/i2002-00299-3 .

Lac, E.; Barthes-Biesel, D. . Deformation of a capsule in simple shear flow: effect of membrane prestress . Phys. Fluids , 2005 . 17 8 .

Villone, M. M.; Hulsen, M. A.; Anderson, P. D.; Maffettone, P. L. . Simulations of deformable systems in fluids under shear flow using an arbitrary Lagrangian Eulerian technique . Comput. Fluids , 2014 . 90 88 - 100 . DOI: 10.1016/j.compfluid.2013.11.016 http://doi.org/10.1016/j.compfluid.2013.11.016 .

Pal, A.; Khakhar, D. V. . Breakage of vesicles in a simple shear flow . Soft Matter , 2019 . 15 1979 - 1987 . DOI: 10.1039/C8SM01501E http://doi.org/10.1039/C8SM01501E .

Abkarian, M.; Faivre, M.; Viallat, A. . Swinging of red blood cells under shear flow . Phys. Rev. Lett. , 2007 . 98 4 .

Abkarian, M.; Viallat, A. . Vesicles and red blood cells in shear flow . Soft Matter , 2008 . 4 653 - 657 . DOI: 10.1039/b716612e http://doi.org/10.1039/b716612e .

Dupire, J.; Socol, M.; Viallat, A. . Full dynamics of a red blood cell in shear flow . Proc. Natl. Acad. Sci. U. S. A. , 2012 . 109 20808 - 20813 . DOI: 10.1073/pnas.1210236109 http://doi.org/10.1073/pnas.1210236109 .

Doddi, S. K.; Bagchi, P. . Lateral migration of a capsule in a plane Poiseuille flow in a channel . Int. J. Multiph. Flow , 2008 . 34 966 - 986 . DOI: 10.1016/j.ijmultiphaseflow.2008.03.002 http://doi.org/10.1016/j.ijmultiphaseflow.2008.03.002 .

Wu, S. H.; Sankhagowit, S.; Biswas, R.; Wu, S. Y.; Povinelli, M. L.; Malmstadt, N. . Viscoelastic deformation of lipid bilayer vesicles . Soft Matter , 2015 . 11 7385 - 7391 . DOI: 10.1039/C5SM01565K http://doi.org/10.1039/C5SM01565K .

Li, J.; Lykotrafitis, G.; Dao, M.; Suresh, S. . Cytoskeletal dynamics of human erythrocyte . Proc. Natl. Acad. Sci. U. S. A. , 2007 . 104 4937 - 4942 . DOI: 10.1073/pnas.0700257104 http://doi.org/10.1073/pnas.0700257104 .

Souli, M.; Ouahsine, A.; Lewin, L. . ALE formulation for fluid-structure interaction problems . Comput. Meth. Appl. Mech. Eng. , 2000 . 190 659 - 675 . DOI: 10.1016/S0045-7825(99)00432-6 http://doi.org/10.1016/S0045-7825(99)00432-6 .

Freund, J. B. . The flow of red blood cells through a narrow spleen-like slit . Phys. Fluids , 2013 . 25 18 .

Gubspun, J.; Gires, P. Y.; de Loubens, C.; Barthes-Biesel, D.; Deschamps, J.; Georgelin, M.; Leonetti, M.; Leclerc, E.; Edwards-Levy, F.; Salsac, A. V. . Characterization of the mechanical properties of cross-linked serum albumin microcapsules: effect of size and protein concentration . Colloid Polym. Sci. , 2016 . 294 1381 - 1389 . DOI: 10.1007/s00396-016-3885-8 http://doi.org/10.1007/s00396-016-3885-8 .

Varchanis, S.; Dimakopoulos, Y.; Wagner, C.; Tsamopoulos, J. . How viscoelastic is human blood plasma? . Soft Matter , 2018 . 14 4238 - 4251 . DOI: 10.1039/C8SM00061A http://doi.org/10.1039/C8SM00061A .

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