Tough Polyion Complex Hydrogel Films of Natural Polysaccharides

Feng-bo Zhu; Hai-chao Yu; Wen-xi Lei; Ke-feng Ren; Jin Qian; Zi-liang Wu; Qiang Zheng

doi:10.1007/s10118-017-1977-7

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Tough Polyion Complex Hydrogel Films of Natural Polysaccharides

Papers | Updated：2021-02-18

- Tough Polyion Complex Hydrogel Films of Natural Polysaccharides
- Tough Polyion Complex Hydrogel Films of Natural Polysaccharides
- Chinese Journal of Polymer Science 2017年35卷第10期页码：1276-1285
- Affiliations：
  
  a.Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
  b.Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province, Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, China
- Author bio：
  
  Zi-liang Wu (吴子良), E-mail:wuziliang@zju.edu.cn
- Funds：
  
  the National Natural Science Foundation of China(51403184);Scientific Research Foundation for the Returned Overseas Chinese Scholars(J20141135);Fundamental Research Funds for the Central Universities of China
- DOI：10.1007/s10118-017-1977-7
  中图分类号：
- 收稿：2017-04-16，
  
  修回：2017-5-16，
  
  录用：2017-5-17，
  
  纸质出版：2017-10-05
- Accepted：
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Feng-bo Zhu, Hai-chao Yu, Wen-xi Lei, 等. Tough Polyion Complex Hydrogel Films of Natural Polysaccharides[J]. Chinese Journal of Polymer Science, 2017,35(10):1276-1285.

Feng-bo Zhu, Hai-chao Yu, Wen-xi Lei, et al. Tough Polyion Complex Hydrogel Films of Natural Polysaccharides[J]. Chinese Journal of Polymer Science, 2017, 35(10): 1276-1285.
Feng-bo Zhu, Hai-chao Yu, Wen-xi Lei, 等. Tough Polyion Complex Hydrogel Films of Natural Polysaccharides[J]. Chinese Journal of Polymer Science, 2017,35(10):1276-1285. DOI： 10.1007/s10118-017-1977-7.

Feng-bo Zhu, Hai-chao Yu, Wen-xi Lei, et al. Tough Polyion Complex Hydrogel Films of Natural Polysaccharides[J]. Chinese Journal of Polymer Science, 2017, 35(10): 1276-1285. DOI： 10.1007/s10118-017-1977-7.

摘要

Abstract

The developments of tough hydrogels in recent years have greatly expanded the applications of hydrogels as structural materials. However

most of the tough hydrogels are made of synthetic polymers. To develop biopolymer-based tough hydrogels has both fundamental and practical significances. Here we report a series of polysaccharides-based tough hydrogel films prepared by polyion complexation and solvent evaporation of chondroitin sulfate (CS) and protonated chitosan (CHT) solutions with different weight ratios. The obtained CS/CHT gel films with thickness of 40-80 μm and water content of 66 wt%-81 wt% possess excellent mechanical properties

with tensile breaking stress and breaking strain being 0.4-3 MPa and 160%-320%

respectively. We found that in the mixture solutions there are large amounts of excess CHT in terms of charges; after swelling the films in water

the acetic acid

which is used to protonate the amino groups of CHT

diffuses out of the gel matrix

enhancing the intermolecular interactions between CHT molecules and thus improving the mechanical properties of gel films

besides the ionic bonds between CS and CHT. Antimicrobial tests also showed that the gel films with low weight ratio of CS to CHT

corresponding to the case with excess CHT

have evident antimicrobial effect. These CS/CHT gel films with good mechanical properties and antimicrobial effect should extend the applications of hydrogels in biomedical fields.

关键词

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references

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