Polypeptide Brushes Grown via Surface-initiated Ring-opening Polymerization of -Amino Acid N-Carboxyanhydrides
REVIEW|Updated:2021-06-21
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Polypeptide Brushes Grown via Surface-initiated Ring-opening Polymerization of -Amino Acid N-Carboxyanhydrides
Polypeptide Brushes Grown via Surface-initiated Ring-opening Polymerization of α-Amino Acid N-Carboxyanhydrides
Chinese Journal of Polymer Science2015年33卷第7期 页码:931-946
Affiliations:
a.School of Polymer Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
b.Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
c.École Polytechnique Fédérale de Lausanne (EPFL), Institut des Matériaux and Institut des Sciences et Ingénierie Chimiques, Laboratoire des Polymères, Bâtiment MXD, Station 12, CH-1015 Lausanne, Switzerland
Author bio:
**Zhibo Li (李志波), E-mail: zbli@qust.edu.cn
Harm-Anton Klok, E-mail: harm-anton.klok@epfl.ch
Funds:
Sino-Swiss Science and Technology Cooperation(EG41-092011)
Polypeptide brushes are attractive platforms to generate functional and responsive interfaces that are of potential interest due to their possible biodegradability
biocompatibility and tunable secondary structures. Surface-initiated ring-opening polymerization (SI-ROP) of
α
-amino acid
N
-carboxyanhydrides represents a powerful and versatile strategy to generate polypeptide brushes. This review is an attempt to capture the state-of-the-art in this field and highlights the latest developments in several selected areas. In addition to presenting an overview of the synthetic methods that have been used to generate polypeptide brushes
via
SI-ROP
this article will discuss the preparation of patterned polypeptide brushes
the conformational properties of surface-tethered polypeptides
ways to control chain orientation at surfaces as well as properties and applications of these thin polymer films.
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相关作者
Jun-Yu Zhang
Jia-Yi Cai
Dong-Hui Zhang
Long-Qiang Liu
Zhong-Hua Zhi
Bing Li
Qi Chen
Run-Hui Liu
相关机构
State Key Laboratory of Molecular Engineering of Polymers, Fudan University
Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences
State Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology
Key Laboratory of Medical Electronics and Digital Health of Zhejiang Province, Jiaxing University
College of Biological, Chemical Sciences and Engineering, Jiaxing University