BIOMIMETIC SURFACE PREPARATION OF INERT POLYMER FILMS VIA GRAFTING LONG MONOALKYL CHAIN PHOSPHATIDYLCHOLINE
PAPER|Updated:2023-01-03
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BIOMIMETIC SURFACE PREPARATION OF INERT POLYMER FILMS VIA GRAFTING LONG MONOALKYL CHAIN PHOSPHATIDYLCHOLINE
BIOMIMETIC SURFACE PREPARATION OF INERT POLYMER FILMS VIA GRAFTING LONG MONOALKYL CHAIN PHOSPHATIDYLCHOLINE
Chinese Journal of Polymer Science2012年30卷第2期 页码:190-198
Affiliations:
College of Polymer Science and Engineering, Sichuan Unversity, State key Laboratory of Polymer Materials Engineering, Chengdu 610065, China
Author bio:
**Jie-hua Li (李洁华), E-mail: jiehua_li@scu.edu.cn
Hong Tan (谭 鸿), E-mail: hongtan@scu.edu.cn
Funds:
National Natural Science Foundation of China(20804025;50673063);Program for the New-Century Excellent Talents of Ministry of Education of China(NCET-08-0381);Sichuan Provincial Science Fund for Distinguished Young Scholars(09ZQ026-024)
Peng-jun Wan, Dong-sheng Tan, Zheng-sheng Li, 等. BIOMIMETIC SURFACE PREPARATION OF INERT POLYMER FILMS VIA GRAFTING LONG MONOALKYL CHAIN PHOSPHATIDYLCHOLINE[J]. Chinese Journal of Polymer Science, 2012,30(2):190-198. DOI: 10.1007/s10118-012-1111-9.
Peng-jun Wan, Dong-sheng Tan, Zheng-sheng Li, et al. BIOMIMETIC SURFACE PREPARATION OF INERT POLYMER FILMS VIA GRAFTING LONG MONOALKYL CHAIN PHOSPHATIDYLCHOLINE[J]. Chinese Journal of Polymer Science, 2012, 30(2): 190-198. DOI: 10.1007/s10118-012-1111-9.
Peng-jun Wan, Dong-sheng Tan, Zheng-sheng Li, 等. BIOMIMETIC SURFACE PREPARATION OF INERT POLYMER FILMS VIA GRAFTING LONG MONOALKYL CHAIN PHOSPHATIDYLCHOLINE[J]. Chinese Journal of Polymer Science, 2012,30(2):190-198. DOI: 10.1007/s10118-012-1111-9.DOI:
Peng-jun Wan, Dong-sheng Tan, Zheng-sheng Li, et al. BIOMIMETIC SURFACE PREPARATION OF INERT POLYMER FILMS VIA GRAFTING LONG MONOALKYL CHAIN PHOSPHATIDYLCHOLINE[J]. Chinese Journal of Polymer Science, 2012, 30(2): 190-198. DOI: 10.1007/s10118-012-1111-9.DOI:
BIOMIMETIC SURFACE PREPARATION OF INERT POLYMER FILMS VIA GRAFTING LONG MONOALKYL CHAIN PHOSPHATIDYLCHOLINE
To explore construction of novel mimicking biomembrane on biomaterials surfaces
a new polymerizable phosphatidylcholine containing a long monoalkyl chain ended with acryl group (AASOPC) was designed and synthesized
which was easily derived from the terminal amino group of 9-(2-amino-ethylcarbamoyl)-nonyl-1-phosphatidyl-choline (ASOPC) reacting with acryloyl chloride. The obtained AASOPC was grafted on poly(ethylene terephthalate) (PET)
via
surface-initiated atom-transfer radical polymerization (SI-ATRP) to form mimicking biomembrane. These modified surface structures of PET were investigated using water contact angle (WAC)
X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM). The results indicated that the new mimicking phosphatidylcholine biomembrane could be prepared on inert polymer surfaces by using the acryloyl phosphatidylcholine (AASOPC)
via
surface-initiated atom transfer radical polymerization (SI-ATRP).
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