TEMPERATURE RESPONSIVE METHACRYLAMIDE POLYMERS WITH ANTIBACTERIAL ACTIVITY

Bor-Kuan Chen; Shuen-Hung Lo; Shu-Feng Lee

doi:10.1007/s10118-010-9129-3

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TEMPERATURE RESPONSIVE METHACRYLAMIDE POLYMERS WITH ANTIBACTERIAL ACTIVITY

Papers | Updated：2021-06-21

- TEMPERATURE RESPONSIVE METHACRYLAMIDE POLYMERS WITH ANTIBACTERIAL ACTIVITY
- TEMPERATURE RESPONSIVE METHACRYLAMIDE POLYMERS WITH ANTIBACTERIAL ACTIVITY
- 高分子科学（英文版） 2010年28卷第4期页码：607-613
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- DOI：10.1007/s10118-010-9129-3
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- 纸质出版：2010-07-20
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Bor-Kuan Chen, Shuen-Hung Lo, Shu-Feng Lee. TEMPERATURE RESPONSIVE METHACRYLAMIDE POLYMERS WITH ANTIBACTERIAL ACTIVITY[J]. 高分子科学（英文版）, 2010,28(4):607-613.

Bor-Kuan Chen, Shuen-Hung Lo, Shu-Feng Lee. TEMPERATURE RESPONSIVE METHACRYLAMIDE POLYMERS WITH ANTIBACTERIAL ACTIVITY[J]. 2010, 28(4): 607-613.
Bor-Kuan Chen, Shuen-Hung Lo, Shu-Feng Lee. TEMPERATURE RESPONSIVE METHACRYLAMIDE POLYMERS WITH ANTIBACTERIAL ACTIVITY[J]. 高分子科学（英文版）, 2010,28(4):607-613. DOI： 10.1007/s10118-010-9129-3.

Bor-Kuan Chen, Shuen-Hung Lo, Shu-Feng Lee. TEMPERATURE RESPONSIVE METHACRYLAMIDE POLYMERS WITH ANTIBACTERIAL ACTIVITY[J]. 2010, 28(4): 607-613. DOI： 10.1007/s10118-010-9129-3.

摘要

A new methacrylamide monomer

hexylamine methacrylamide (MAHA)

was synthesized and used in polymerizations. The homopolymer of MAHA and its copolymers were synthesized by free radical polymerization techniques with N-isopropyl acrylamide (NIPAAm) in two different compositions. The quaternization of the homopolymer and copolymers were carried out using 1-bromopropane. The copolymers with NIPAAm and a low MAHA content showed temperature-responsive behavior in an aqueous environment. The lower critical solution temperatures (LCSTs) of these polymers varied between 32°C and 44°C. The LCSTs of quaternized copolymers were higher than those of neutral copolymers because they were more hydrophilic. The obtained homopolymers and copolymers were tested for antibacterial activities against S. aureus and E. coli. The quaternized water-soluble copolymers showed antibacterial activities against S. aureus. The quaternization resulted in the synthesis of both antibacterial and temperature-responsive copolymers.

Abstract

A new methacrylamide monomer

hexylamine methacrylamide (MAHA)

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