TUNED MECHANICAL PROPERTIES ACHIEVED BY VARYING POLYMER STRUCTURE-KNOWLEDGE THAT GENERATES NEW MATERIALS FOR TISSUE ENGINEERING
Invited Paper|Updated:2021-06-21
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TUNED MECHANICAL PROPERTIES ACHIEVED BY VARYING POLYMER STRUCTURE-KNOWLEDGE THAT GENERATES NEW MATERIALS FOR TISSUE ENGINEERING
TUNED MECHANICAL PROPERTIES ACHIEVED BY VARYING POLYMER STRUCTURE-KNOWLEDGE THAT GENERATES NEW MATERIALS FOR TISSUE ENGINEERING
高分子科学(英文版)2007年第2期 页码:113-118
Affiliations:
1. Department of Fiber and Polymer Technology Royal Institute of Technology
2. Stockholm
3. Sweden
Author bio:
Funds:
This work was supported by the Swedish Foundation for Strategic Research(No. A302:132).()
DOI:
中图分类号:O631.3
纸质出版:2007
Accepted:
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[1]Anna Finne Wistrand,Ann-Christine Albertsson.TUNED MECHANICAL PROPERTIES ACHIEVED BY VARYING POLYMER STRUCTURE-KNOWLEDGE THAT GENERATES NEW MATERIALS FOR TISSUE ENGINEERING[J].Chinese Journal of Polymer Science,2007(02):113-118.
TUNED MECHANICAL PROPERTIES ACHIEVED BY VARYING POLYMER STRUCTURE-KNOWLEDGE THAT GENERATES NEW MATERIALS FOR TISSUE ENGINEERING[J]. 2007, (2): 113-118.
[1]Anna Finne Wistrand,Ann-Christine Albertsson.TUNED MECHANICAL PROPERTIES ACHIEVED BY VARYING POLYMER STRUCTURE-KNOWLEDGE THAT GENERATES NEW MATERIALS FOR TISSUE ENGINEERING[J].Chinese Journal of Polymer Science,2007(02):113-118.DOI:
TUNED MECHANICAL PROPERTIES ACHIEVED BY VARYING POLYMER STRUCTURE-KNOWLEDGE THAT GENERATES NEW MATERIALS FOR TISSUE ENGINEERING[J]. 2007, (2): 113-118.DOI:
TUNED MECHANICAL PROPERTIES ACHIEVED BY VARYING POLYMER STRUCTURE-KNOWLEDGE THAT GENERATES NEW MATERIALS FOR TISSUE ENGINEERING
<正>By changing both the monomer composition and the polymer structure
we have varied the mechanical properties of resorbable polymers. The polymers were synthesized by ring-opening polymerization using L-lactide (LLA)
ε-caprolactone (εCL)
trimethylene carbonate (TMC) and 1
5-dioxepan-2-one (DXO) as monomers. Well-defined triblock copolymers
microblock copolymers and networks have been evaluated
and comparisons between them show that it is possible to tune the mechanical properties. Triblock copolymers with an amorphous middle block of poly( 1
5-dioxepan-2-one) (PDXO) and semi-crystalline end-blocks of poly(ε-caprolactone) (PCL) were stronger and had a higher strain at break than triblock copolymers with poly(L-lactide) (PLLA) as end-blocks. Polymers with both DXO and TMC in the amorphous middle-block and PLLA as end-blocks showed a lower stress at break
but the material gained elasticity
a property which is very valuable in tissue engineering. Mechanical properties of networks
synthesized by a novel method
containing PDXO and PCL are also presented. Although it is difficult to compare them with the uncross-linked polymers
this is an additional way to modify and widen the properties.
Abstract
By changing both the monomer composition and the polymer structure
we have varied the mechanical properties of resorbable polymers. The polymers were synthesized by ring-opening polymerization using L-lactide (LLA)
ε-caprolactone (εCL)
trimethylene carbonate (TMC) and 1
5-dioxepan-2-one (DXO) as monomers. Well-defined triblock copolymers
microblock copolymers and networks have been evaluated
and comparisons between them show that it is possible to tune the mechanical properties. Triblock copolymers with an amorphous middle block of poly( 1
5-dioxepan-2-one) (PDXO) and semi-crystalline end-blocks of poly(ε-caprolactone) (PCL) were stronger and had a higher strain at break than triblock copolymers with poly(L-lactide) (PLLA) as end-blocks. Polymers with both DXO and TMC in the amorphous middle-block and PLLA as end-blocks showed a lower stress at break
but the material gained elasticity
a property which is very valuable in tissue engineering. Mechanical properties of networks
synthesized by a novel method
containing PDXO and PCL are also presented. Although it is difficult to compare them with the uncross-linked polymers
this is an additional way to modify and widen the properties.
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