NOVEL HYBRID GENE VECTOR STABILIZED BY CROSS-LINKING WITH GOLD NANOPARTICLES

You-xiang Wang a; Ying Zhu c; Jia-cong Shen a

Your Location：

Home >

Browse articles >

NOVEL HYBRID GENE VECTOR STABILIZED BY CROSS-LINKING WITH GOLD NANOPARTICLES

Note | Updated：2021-06-21

- NOVEL HYBRID GENE VECTOR STABILIZED BY CROSS-LINKING WITH GOLD NANOPARTICLES
- NOVEL HYBRID GENE VECTOR STABILIZED BY CROSS-LINKING WITH GOLD NANOPARTICLES
- 高分子科学（英文版） 2008年26卷第4期页码：507-512
- Affiliations：
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：2008-07-20
- Accepted：
Scan QR Code
You-xiang Wang a, Ying Zhu c, Jia-cong Shen a. NOVEL HYBRID GENE VECTOR STABILIZED BY CROSS-LINKING WITH GOLD NANOPARTICLES[J]. 高分子科学（英文版）, 2008,26(4):507-512.

You-xiang Wang a, b, Ying Zhu c. NOVEL HYBRID GENE VECTOR STABILIZED BY CROSS-LINKING WITH GOLD NANOPARTICLES[J]. 2008, 26(4): 507-512.
You-xiang Wang a, Ying Zhu c, Jia-cong Shen a. NOVEL HYBRID GENE VECTOR STABILIZED BY CROSS-LINKING WITH GOLD NANOPARTICLES[J]. 高分子科学（英文版）, 2008,26(4):507-512. DOI：

You-xiang Wang a, b, Ying Zhu c. NOVEL HYBRID GENE VECTOR STABILIZED BY CROSS-LINKING WITH GOLD NANOPARTICLES[J]. 2008, 26(4): 507-512. DOI：

摘要

Enhanced stability of polyplexes in physiological condition was an important prerequisite for successful systemic gene delivery. Herein novel method was reported to develop stable gene vector by nanotechnology. Thiolated polyplexes were constructed and then cross-linked with gold nanoparticles (AuNPs) by gold-thiol interactions. TEM pictures showed that AuNPs were attached to the shell of spherical polyplexes. The hybrid gene vector was stable enough in physiological condition and maintained efficient transfection

which showed great potential in gene delivery research and application.

Abstract

which showed great potential in gene delivery research and application.

关键词

Keywords

references

浏览量

175

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Enhanced Segment Mobility Promotes Stereocomplex Crystallization in Polymer Blends via Elevated Segmental Miscibility

Preparation and Chiral Recognition Ability of Crystalline Cellulose Phenylcarbamate

Improvements of Hydrophobicity and Toughness of Epoxy Coatings Modified with Hydroxyl-terminated Fluororubber

End-group and Side-chain Dual-engineering of Selenium-fused Acceptors for 20.08% Efficiency Polymer Solar Cells with Low Energy Loss

Manipulating Hierarchical Aggregation Structure via Film-forming Kinetics Enables Organic Photovoltaics over 20% Efficiency