SYNTHESIS OF OLIGOMERS CONTAINING 5-FLUOROURACIL

PIAO Aichih; SUN Shumen

Your Location：

Home >

Browse articles >

SYNTHESIS OF OLIGOMERS CONTAINING 5-FLUOROURACIL

Papers | Updated：2021-06-21

- SYNTHESIS OF OLIGOMERS CONTAINING 5-FLUOROURACIL
- SYNTHESIS OF OLIGOMERS CONTAINING 5-FLUOROURACIL
- 高分子科学（英文版） 1983年1卷第2期页码：196-199
- Affiliations：
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1983-11-20
- Accepted：
Scan QR Code
PIAO Aichih, SUN Shumen. SYNTHESIS OF OLIGOMERS CONTAINING 5-FLUOROURACIL[J]. 高分子科学（英文版）, 1983,1(2):196-199.

PIAO Aichih, SUN Shumen. SYNTHESIS OF OLIGOMERS CONTAINING 5-FLUOROURACIL[J]. 1983, 1(2): 196-199.
PIAO Aichih, SUN Shumen. SYNTHESIS OF OLIGOMERS CONTAINING 5-FLUOROURACIL[J]. 高分子科学（英文版）, 1983,1(2):196-199. DOI：

PIAO Aichih, SUN Shumen. SYNTHESIS OF OLIGOMERS CONTAINING 5-FLUOROURACIL[J]. 1983, 1(2): 196-199. DOI：

摘要

The condensation oligomers of 5-fluorouracil were prepared by reaction of 2

4-bis-(trimethyl-silyloxy)-5-fluoropyrimidine) with various dicarboxylic chlorides

e.g.The structures of obtained oligomers were characterized by IR and the oligomers were then hydrolyzed in acid

alkaline and neutral media at room temperature respectively. The amount of 5-fluorouracil released was quantitated by measuring its UV absorbance at 265.5nm. However in the case of oligomers containing phenylene moiety

5-fluorouracil was not detected when the hydrolysis was conducted in acid or neutral medium

while in the case of oligomers containing methylene moiety

hydrolysis proceeded easily in acid

alkaline and neutral media.

Abstract

The condensation oligomers of 5-fluorouracil were prepared by reaction of 2

4-bis-(trimethyl-silyloxy)-5-fluoropyrimidine) with various dicarboxylic chlorides

e.g.The structures of obtained oligomers were characterized by IR and the oligomers were then hydrolyzed in acid

5-fluorouracil was not detected when the hydrolysis was conducted in acid or neutral medium

while in the case of oligomers containing methylene moiety

hydrolysis proceeded easily in acid

alkaline and neutral media.

关键词

Keywords

references

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Two-way Shape Memory Effect of Polycaprolactone-based Polyurethane via Synergistic Role of Hydrogen Bonding and Crystallization Tuned by Malic Acid

Tunable Circularly Polarized Luminescence of Helical Poly(phenylacetylene)s via Side-chain-to-Backbone Förster Resonance Energy Transfer

Manipulating Hierarchical Aggregation Structure via Film-forming Kinetics Enables Organic Photovoltaics over 20% Efficiency

Multiple-Responsive Chiral Hydrogels from Helical Dendronized Poly(phenylacetylene)s

Porous Organic Polymers for Photocatalytic Hydrogen Peroxide Production: Recent Advances and Future Perspectives