Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection

Jiao He; Hua-Jian Song; Zuo-An Liu; Bing-Li Jiang; Yong-Yang Gong; Wang-Zhang Yuan

doi:10.1007/s10118-024-3161-1

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Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection

RESEARCH ARTICLE | Updated：2024-11-04

- Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection
- Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection
- 高分子科学（英文版） 2024年42卷第11期页码：1679-1689
- Affiliations：
  
  a.Guangxi Key Laboratory of Optical and Electronic Materials and Devices, College of Materials Science and Engineering, Guilin University of Technology, Guilin 541004, China
  b.College of Pharmacy, Guilin Medical University, Guilin 541199, China
  c.School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
- Author bio：
  
  yygong@glut.edu.cn (Y.Y.G.)
  wzhyuan@sjtu.edu.cn (W.Z.Y.)
- Funds：
  
  This work was financially supported by the National Natural Science Foundation of China (No. 52163017), Project of Guangxi Natural Science Foundation (No. 2021GXNSFAA220047), the project of Thousand Outstanding Young Teachers' Training in Higher Education Institutions of Guangxi and the Open Project Program of Guangxi Key Laboratory of Optical and Electronic Materials and Devices (No. 20AA-2).;Electronic supplementary information (ESI) is available free of charge in the online version of this article at http://doi.org/10.1007/s10118-024-3161-1.
- DOI：10.1007/s10118-024-3161-1
  中图分类号：
- 纸质出版日期：2024-11-30，
  
  网络出版日期：2024-08-20，
  
  收稿日期：2024-03-08，
  
  修回日期：2024-04-27，
  
  录用日期：2024-05-12
- Accepted：
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He, J.; Song, H. J.; Liu, Z. A.; Jiang, B. L.; Gong, Y. Y.; Yuan, W. Z. Efficient and pH-sensitive nonconventional luminescent polymers for cellular imaging and ion detection. Chinese J. Polym. Sci. 2024, 42, 1679–1689

Jiao He, Hua-Jian Song, Zuo-An Liu, et al. Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection. [J]. Chinese Journal of Polymer Science, 2024,42(11):1679-1689.
He, J.; Song, H. J.; Liu, Z. A.; Jiang, B. L.; Gong, Y. Y.; Yuan, W. Z. Efficient and pH-sensitive nonconventional luminescent polymers for cellular imaging and ion detection. Chinese J. Polym. Sci. 2024, 42, 1679–1689 DOI： 10.1007/s10118-024-3161-1.

Jiao He, Hua-Jian Song, Zuo-An Liu, et al. Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection. [J]. Chinese Journal of Polymer Science, 2024,42(11):1679-1689. DOI： 10.1007/s10118-024-3161-1.

摘要

Nonconventional luminescent polymers exhibit remarkably high luminescence efficiency

reaching up to 9.2% in dilute solutions (0.1 mg/mL)

and their optical properties are highly responsive to a range of variables

including pH

excitation wavelength

concentration

temperature and metal ions. Due to these unique optical properties and their good biocompatibility

these materials have emerged as a promising class of materials for cell imaging applications.

Abstract

Nonconventional luminescent materials (NLMs) are a type of organic luminescent materials that does not contain aromatic units. Due to the simplicity of the synthesis process

mild reaction conditions

good hydrophilicity and biological compatibility

NLMs have attracted much attention. Nevertheless

numerous reports indicate that NLMs can only effectively luminesce at high concentrations and in solid state

which limits their applicability in the field of cell imaging. This study addresses this limitation by designing and synthesizing oligomers P1

P2 and P3 using ethylene glycol diglycidyl ether and amine compounds containing ethylene groups. These oligomers exhibit remarkable luminescence efficiency reaching as high as 9.2% in dilute solutions (0.1 mg/mL)

making them among the best NLMs in this category. Furthermore

the synthesized oligomers exhibit excitation wavelength-dependent and concentration-dependent luminescence intensity

fluorescence response to temperature and pH changes

as well as the ability to identify Fe

and Mo

in dilute solutions. These characteristics render them potentially useful in the for cell imaging.

关键词

Keywords

ClusteroluminescenceNonconventional luminescent materialsDilute solutionsCell imaging

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