Helium Plasma Effects on Polymer Surfaces: from Plasma Parameters and Surface Properties towards Bioengineering Applications

Andrei Vasile Nastuta; Maria Butnaru; Byron Cheatham; Ramona Huzum; Vasile Tiron; Ionut Topala

doi:10.1007/s10118-024-3147-z

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Helium Plasma Effects on Polymer Surfaces: from Plasma Parameters and Surface Properties towards Bioengineering Applications

RESEARCH ARTICLE | Updated：2024-08-06

- Helium Plasma Effects on Polymer Surfaces: from Plasma Parameters and Surface Properties towards Bioengineering Applications
- Helium Plasma Effects on Polymer Surfaces: from Plasma Parameters and Surface Properties towards Bioengineering Applications
- 高分子科学（英文版） 2024年42卷第8期页码：1156-1166
- Affiliations：
  
  a.Physics and Biophysics Education Research Laboratory (P & B-EduResLab), Biomedical Science Department, Faculty of Medical Bioengineering, ‘Grigore T. Popa’ University of Medicine and Pharmacy Iasi, M. Kogalniceanu 9-13, Iasi 700454, Romania
  b.Faculty of Medical Bioengineering, ‘Grigore T. Popa’ University of Medicine and Pharmacy Iasi, M. Kogalniceanu 9-13, Iasi 700454, Romania
  c.Cytoviva, Inc., 570 Devall Drive Suite 301, Auburn 36832, AL, USA
  d.Integrated Center of Environmental Science Studies in the North-Eastern Development Region (CERNESIM), Department of Exact and Natural Sciences, Institute of Interdisciplinary Research, ‘Alexandru Ioan Cuza’ University of Iasi, Blvd. Carol I no. 11, Iasi 700506, Romania
  e.Research Center on Advanced Materials and Technologies (RAMTECH), Department of Exact and Natural Sciences, Institute of Interdisciplinary Research, ‘Alexandru Ioan Cuza’ University of Iasi, Blvd. Carol I no. 11, Iasi 700506, Romania
  f.Iasi Plasma Advanced Research Center (IPARC), Faculty of Physics, ‘Alexandru Ioan Cuza’ University of Iasi, Blvd. Carol I no. 11, Iasi 700506, Romania
- Author bio：
  
  andrei.nastuta@gmail.com
- Funds：
  
  This work was financially supported by UEFISCDI, PNCDI III, project PN-III-P1-1.1-TE-2021 (No. 150/09.06.2022). This work was related to COST Action CA20114, PlasTHER-Therapeutical Applications of Cold Plasmas, supported by COST (European Cooperation in Science and Technology, available online: https://www.cost.eu, accessed on 20 November 2023). A.V.N. also acknowledges fruitful discussion with the members of CEEPUS CIII-AT-0063, Applications and diagnostics of electric plasmas ( https://www.ceepus.info/).
- DOI：10.1007/s10118-024-3147-z
  中图分类号：
- 纸质出版日期：2024-08-01，
  
  网络出版日期：2024-05-23，
  
  收稿日期：2024-01-07，
  
  修回日期：2024-03-23，
  
  录用日期：2024-04-16
- Accepted：
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Nastuta, A. V.; Butnaru, M.; Cheatham, B.; Huzum, R.; Tiron, V.; Topala, I. Helium plasma effects on polymer surfaces: from plasma parameters and surface properties towards bioengineering applications. Chinese J. Polym. Sci. 2024, 42, 1156–1166

Andrei Vasile Nastuta, Maria Butnaru, Byron Cheatham, et al. Helium Plasma Effects on Polymer Surfaces: from Plasma Parameters and Surface Properties towards Bioengineering Applications[J]. Chinese Journal of Polymer Science, 2024,42(8):1156-1166.
Nastuta, A. V.; Butnaru, M.; Cheatham, B.; Huzum, R.; Tiron, V.; Topala, I. Helium plasma effects on polymer surfaces: from plasma parameters and surface properties towards bioengineering applications. Chinese J. Polym. Sci. 2024, 42, 1156–1166 DOI： 10.1007/s10118-024-3147-z.

Andrei Vasile Nastuta, Maria Butnaru, Byron Cheatham, et al. Helium Plasma Effects on Polymer Surfaces: from Plasma Parameters and Surface Properties towards Bioengineering Applications[J]. Chinese Journal of Polymer Science, 2024,42(8):1156-1166. DOI： 10.1007/s10118-024-3147-z.

摘要

A source of cold plasma

at atmospheric pressure

in helium

is used for the direct or indirect exposure of organic matter for subsequent interaction with living cells

which are studied using fluorescence or hyperspectral microscopy in order to investigate the after-plasma exposure biocompatibility of materials.

Abstract

Plasma treatment is necessary to optimize the performance of biomaterial surfaces. It enhances and regulates the performance of biomaterial surfaces

creating an effective interface with the human body. Plasma treatments have the ability to modify the chemical composition and physical structure of a surface while leaving its properties unaffected. They possess the ability to modify material surfaces

eliminate contaminants

conduct investigations on cancer therapy

and facilitate wound healing. The subject of study in question involves the integration of plasma science and technology with biology and medicine. Using a helium plasma jet source

applying up to 18 kV

with an average power of 10 W

polymer foils were treated for 60 s. Plasma treatment has the ability to alter the chemical composition and physical structure of a surface while maintaining its quality. This investigation involved the application of helium plasma at atmospheric pressure to polyamide 6 and polyethylene terephthalate sheets. The inquiry involves monitoring and assessing the plasma source and polymer materials

as well as analyzing the impacts of plasma therapy. Calculating the mean power of the discharge aids in assessing the economic efficacy of the plasma source. Electric discharge in helium at atmospheric pressure has beneficial effects in technology

where it increases the surface free energy of polymer materials. In biomedicine

it is used to investigate cytotoxicity and cell survival

particularly in direct blood exposure situations that can expedite coagulation. Comprehending the specific parameters that influence the plasma source in the desired manner for the intended application is of utmost importance.

关键词

Keywords

Atmopheric pressure plasmasPlasma-polymer interactionPlasma MedicinePlasma diagnosisPolymer characterization

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