Polymer Translocation

Lu-Wei Lu; Zhen-Hua Wang; An-Chang Shi; Yu-Yuan Lu; Li-Jia An

doi:10.1007/s10118-023-2975-6

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Polymer Translocation

REVIEW | Updated：2023-04-21

- Polymer Translocation
- Polymer Translocation
- 高分子科学（英文版） 2023年41卷第5期页码：683-698
- Affiliations：
  
  a.State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
  b.University of Science and Technology of China, Hefei 230026, China
  c.Department of Physics and Astronomy, McMaster University, Hamilton, Ontario L8S4M1, Canada
- Author bio：
  
  yylu@ciac.ac.cn(Y.Y.L.)
  ljan@ciac.ac.cn(L.J.A.)
- Funds：
  
  This work was financially supported by the National Key R&D Program of China (No. 2020YFA0713601), the National Natural Science Foundation of China (Nos. 22073092 and 21790340) and the Programs of Chinese Academy of Sciences (No. QYZDY-SSW-SLH027).;Yu-Yuan Lureceived his Ph.D. degree from the University of Chinese Academy of Sciences (UCAS) in 2016. He was appointed as a full professor at the Changchun Institute of Applied Chemistry (CIAC) in 2021. He has been focusing on two fundamental challenges in the rheology of polymer melts and solutions: (1) the mechanism of flow instabilities and inhomogeneities, and (2) the treatment of hydrodynamic interactions between a chain and solvent molecules. He has led 10 national or provincial scientific research projects and published 46 SCI papers as the first or corresponding author. He was elected as a recipient of the Young Elite Scientist Sponsorship Program by the China Association for Science and Technology in 2016 and was honored as one of the elite members of the Youth Innovation Promotion Association of Chinese Academy of Sciences in 2020. He received the Youth in Rheology Award from the Chinese Chemical Society and the Chinese Society of Theoretical and Applied Mechanics in 2020.Li-Jia Anreceived his Ph.D. in Polymer Chemistry and Physics in 1992 from Jilin University. Then he joined the Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS) and was appointed as a full professor in 1997. He was elected a member of the Chinese Academy of Sciences in 2015. His research interest concerns nonlinear rheology of polymers, dynamics and relaxation of glass-forming liquids, and dynamics of polymer dilute solutions.
- DOI：10.1007/s10118-023-2975-6
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Polymer Translocation[J]. 高分子科学（英文版）, 2023,41(5):683-698.

Lu-Wei Lu, Zhen-Hua Wang, An-Chang Shi, et al. Polymer Translocation[J]. Chinese Journal of Polymer Science, 2023,41(5):683-698.
Polymer Translocation[J]. 高分子科学（英文版）, 2023,41(5):683-698. DOI： 10.1007/s10118-023-2975-6.

Lu-Wei Lu, Zhen-Hua Wang, An-Chang Shi, et al. Polymer Translocation[J]. Chinese Journal of Polymer Science, 2023,41(5):683-698. DOI： 10.1007/s10118-023-2975-6.

摘要

Polymer translocation has been one of challenging research topics in polymer physics. Despite great progresses made in previous studies, many essential problems remain unsolved. This review has expounded some major advances in different aspects of translocation, such as capture process, critical flux, conformational transition, and translocation time.

Abstract

The translocation of a polymer through a pore that is much smaller than its size is a fundamental and actively researched topic in polymer physics. An understanding of the principles governing polymer translocation provides important guidance for various practical applications, such as the separation and purification of polymers, nanopore-based single-molecule deoxyribonucleic acid/ribonucleic acid(DNA/RNA) sequencing, transmembrane transport of DNA or RNA, and infection of bacterial cells by bacteriophages. The past several decades have seen great progresses on the study of polymer translocation. Here we present an overview of theoretical, experimental, and simulational stduies on polymer translocation, focusing on the roles played by several important factors, including initial polymer conformations, external fields, polymer topology and architectures, and confinement degree. We highlight the physical mechanisms of different types of polymer translocations, and the main controversies about the basic rules of translocation dynamics. We compare and contrast the behaviors of force-induced versus flow-induced translocations and the effects of unknotted versus knotted polymers. Finally, we mention several opportunities and challenges in the study of polymer translocation.

关键词

Keywords

Polymer translocationKnotted polymersTranslocation timeCritical flux

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