Backbone Degradable Polymers <italic style="font-style: italic">via</italic> Chain-growth Radical Polymerization

Hai-Wang Lai; Makoto Ouchi

doi:10.1007/s10118-025-3278-x

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Backbone Degradable Polymers via Chain-growth Radical Polymerization

REVIEW | Updated：2025-07-14

- Backbone Degradable Polymers via Chain-growth Radical Polymerization
- Chinese Journal of Polymer Science Vol. 43, Issue 6, Pages: 887-907(2025)
- Affiliations：
  
  a.Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China
  b.Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan
- Author bio：
  
  laihaiwang@gbu.edu.cn (H.W.L.)
  makoto.2v@kyoto-u.ac.jp (M.O.)
- Funds：
- DOI：10.1007/s10118-025-3278-x
  CLC：
- Received：31 October 2024，
  
  Revised：2024-11-23，
  
  Accepted：27 November 2024，
  
  Online First：24 February 2025，
  
  Published：20 May 2025
- Accepted：
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Lai, H. W.; Ouchi, M. Backbone degradable polymers via chain-growth radical polymerization. Chinese J. Polym. Sci. 2025, 43, 887–907

Hai-Wang Lai, Makoto Ouchi. Backbone Degradable Polymers via Chain-growth Radical Polymerization[J]. Chinese Journal of Polymer Science, 2025, 43(6): 887-907. DOI: 10.1007/s10118-025-3278-x.
Lai, H. W.; Ouchi, M. Backbone degradable polymers via chain-growth radical polymerization. Chinese J. Polym. Sci. 2025, 43, 887–907 DOI： 10.1007/s10118-025-3278-x.

Hai-Wang Lai, Makoto Ouchi. Backbone Degradable Polymers via Chain-growth Radical Polymerization[J]. Chinese Journal of Polymer Science, 2025, 43(6): 887-907. DOI: 10.1007/s10118-025-3278-x. DOI：

摘要

This review summarizes recent advances in endowing vinyl polymers with degradability

aiming to reduce their environmental impact and enhance their application in bio-relevant areas.

Abstract

Chain-growth radical polymerization of vinyl monomers is essential for producing a wide range of materials with properties tailored to specific applications. However

the inherent resistance of the polymer's C―C backbone to degradation raises significant concerns regarding long-term environmental persistence

which also limits their potential in biomedical applications. To address these challenges

researchers have developed strategies to either degrade preexisting vinyl polymers or incorporate cleavable units into the backbone to modify them with enhanced degradability. This review explores the various approaches aimed at achieving backbone degradability in chain-growth radical polymerization of vinyl monomers

while also highlighting future research directions for the development of application-driven degradable vinyl polymers.

关键词

Keywords

references

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Backbone Degradable Polymers via Chain-growth Radical Polymerization

DOI：10.1007/s10118-025-3278-x

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