Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes

Zhan Li; Haotian Li; Jianhua Zhang; Xianhu Liu; Zhipeng Gu; Yiwen Li

doi:10.1007/s10118-020-2486-7

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Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes

RAPID COMMUNICATION | Updated：2020-08-25

- Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes
- Chinese Journal of Polymer Science Vol. 38, Issue 11, Pages: 1149-1156(2020)
- Affiliations：
  
  a.College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China
  b.School of Materials Science and Engineering, Xihua University, Chengdu 610039, China
  c.National Engineering Research Center for Advanced Polymer Processing Technology, Zhengzhou University, Zhengzhou 450002, China
- Author bio：
  
  guzhipeng2019@scu.edu.cn (Z.G.)
  ywli@scu.edu.cn (Y.L.)
- Funds：
- DOI：10.1007/s10118-020-2486-7
  CLC：
- Received：11 July 2020，
  
  Revised：2020-7-26，
  
  Accepted：27 July 2020，
  
  Online First：25 August 2020，
  
  Published：14 August 2020
- Accepted：
Scan QR Code
Li, Z.; Li, H.; Zhang, J.; Liu, X.; Gu, Z.; Li, Y. Ultrasmall nanoparticle ROS scavengers based on polyhedral oligomeric silsesquioxanes. Chinese J. Polym. Sci. 2020, 38, 1149–1156

Zhan Li, Haotian Li, Jianhua Zhang, et al. Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes[J]. Chinese Journal of Polymer Science, 2020, 38(11): 1149-1156.
Li, Z.; Li, H.; Zhang, J.; Liu, X.; Gu, Z.; Li, Y. Ultrasmall nanoparticle ROS scavengers based on polyhedral oligomeric silsesquioxanes. Chinese J. Polym. Sci. 2020, 38, 1149–1156 DOI： 10.1007/s10118-020-2486-7.

Zhan Li, Haotian Li, Jianhua Zhang, et al. Ultrasmall Nanoparticle ROS Scavengers Based on Polyhedral Oligomeric Silsesquioxanes[J]. Chinese Journal of Polymer Science, 2020, 38(11): 1149-1156. DOI： 10.1007/s10118-020-2486-7.

摘要

Abstract

Although tremendous efforts have been devoted to the structural and functional tailoring of natural polyphenol-functionalized nanoparticles

preparing ultrasmall sized (

6 nm) particles with precisely-defined structures has remained a grand challenge. In this work

we reported the preparation of ultra-small and precisely structured polyhedral oligomeric silsesquioxanes (POSS)-based polyphenol nanoparticles (T

and T

-GAPOSS) by accurately functionalizing the POSS surface with plant polyphenol gallic acid units

via

thiol-Michael “click” reactions. Those polyphenol nanoparticles exhibited strong free radical scavenging capacity

good biocompatibility and ability to resist cell oxidative damage

which demonstrated great potentials in inhibiting oxidative stress induced pathologies.

关键词

Keywords

references

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