

FOLLOWUS
a.State Key Laboratory of Fine Chemicals, Department of Polymer Science & Materials, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, China
b.Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
c.Department of Chemistry, Carleton University, Ontario K1S 5B6, Canada
wqqiao@dlut.edu.cn (W.Q.Q.)
wwjoy@dlut.edu.cn (Z.Y.W.)
Received:25 December 2019,
Revised:2020-2-9,
Accepted:09 March 2020,
Online First:13 May 2020,
Published:2020-08
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Zhang, Y. L.; Ren, J. T.; Gao, H. Y.; Liu, J. W.; Xia, W. J.; Qiao, W. Q.; Wang, Z. Y. Characterizations and photothermal properties of narrow bandgap conjugated polymer nanoparticles. Chinese J. Polym. Sci. 2020, 38, 814–818
Yu-Lin Zhang, Jun-Tao Ren, Huai-Yu Gao, et al. Characterizations and Photothermal Properties of Narrow Bandgap Conjugated Polymer Nanoparticles[J]. Chinese Journal of Polymer Science, 2020, 38(8): 814-818.
Zhang, Y. L.; Ren, J. T.; Gao, H. Y.; Liu, J. W.; Xia, W. J.; Qiao, W. Q.; Wang, Z. Y. Characterizations and photothermal properties of narrow bandgap conjugated polymer nanoparticles. Chinese J. Polym. Sci. 2020, 38, 814–818 DOI: 10.1007/s10118-020-2420-z.
Yu-Lin Zhang, Jun-Tao Ren, Huai-Yu Gao, et al. Characterizations and Photothermal Properties of Narrow Bandgap Conjugated Polymer Nanoparticles[J]. Chinese Journal of Polymer Science, 2020, 38(8): 814-818. DOI: 10.1007/s10118-020-2420-z.
Photothermal therapy (PTT) is a minimally invasive treatment that kills cancer cells by converting photon energy into heat. The past few decades have witnessed the booming development of photothermal materials
mainly focusing on precious metal nanomaterials and carbon nanomaterials
such as nanogold and silver and nanocarbon materials for near-infrared (NIR) light-triggered PTT. As precious metals are expensive and potentially harmful to humans
exploration and development of a new type of photothermal materials has become a research hotspot in this field. Herein
we report narrow bandgap conjugated polymer nanoparticles (PDPP NPs) based on pyrrolo[3
4-
c
]pyrrole-1
4-dione (DPP) with intense NIR absorption at 900 nm
as well as a photothermal energy conversion efficiency of 75%. This polymer nanoparticle is essentially non-toxic
as the cell viability of mouse remained more than 90%
even when the concentration of PDPP NPs was at 0.5 mg·mL
−1
.
Mi, Y.; Shao, Z. Y.; Vang, J.; Kaidar, O.; Wang, A. Z. . Application of nanotechnology to cancer radiotherapy . Cancer Nano. , 2016 . 7 11 DOI: 10.1186/s12645-016-0024-7 http://doi.org/10.1186/s12645-016-0024-7 .
Zhao, W.; Li, A. H.; Zhang, A. T.; Zheng, Y. W.; Liu, J. Q. . Recent advance in functional-polymer-decorated transional-metal nanomaterials for bioimaging and cancer therapy . Chem. Med. Chem. , 2018 . 13 2134 - 2149 . DOI: 10.1002/cmdc.201800462 http://doi.org/10.1002/cmdc.201800462 .
Zhao, J. Y.; Zhong, D.; Zhou, S. B. . NIR-I-to-NIR-II fluorescent nanomaterials for biomedical imaging and cancer therapy . J. Mater. Chem. B , 2018 . 6 349 .
Li, J. C.; Rao, J. H.; Pu, K. Y. . Recent progress on semiconducting polymer nanoparticles for molecular imaging and cancer phototherapy . Biomaterials , 2018 . 155 217 - 235 . DOI: 10.1016/j.biomaterials.2017.11.025 http://doi.org/10.1016/j.biomaterials.2017.11.025 .
Hyo, S. J.; Verwilst, P.; Sharma, A. . Organic molecule-based photothermal agents: an expanding photothermal therapy universe . Chem. Soc. Rev. , 2018 . 47 2280 DOI: 10.1039/C7CS00522A http://doi.org/10.1039/C7CS00522A .
Cai, Y.; Si, W. L.; Huang, W. . Organic dye based nanoparticles for cancer phototheranostics . Small. , 2018 . 14 1704247 DOI: 10.1002/smll.201704247 http://doi.org/10.1002/smll.201704247 .
Chen, Q.; Xu, L. G.; Liang, C. . Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy . Nat. Commun. , 2016 . 7 13193 DOI: 10.1038/ncomms13193 http://doi.org/10.1038/ncomms13193 .
Liu, Y. J.; Bhattara, P.; Dai, Z. F. . Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer . Chem. Soc. Rev. , 2019 . 48 2053 DOI: 10.1039/C8CS00618K http://doi.org/10.1039/C8CS00618K .
Zhen, X.; Feng, X. H.; Xie, C.; Zheng, Y. J.; Pu, K. Y. . Surface engineering of semiconducting polymer nanoparticles for amplified photoacoustic imaging . Biomaterials , 2017 . 127 97 - 106 . DOI: 10.1016/j.biomaterials.2017.03.003 http://doi.org/10.1016/j.biomaterials.2017.03.003 .
Syama1, S.; Mohanan, P. V. . Comprehensive application of graphene: emphasis on biomedical concerns . Nano-Micro. Lett. , 2019 . 11 6 DOI: 10.1007/s40820-019-0237-5 http://doi.org/10.1007/s40820-019-0237-5 .
Jiang, B. P.; Zhou, B.; Lin, Z. X.; Liang, H.; Shen, X. C. . Recent advances in carbon nanomaterials for cancer phototherapy . Chem. Eur. J. , 2019 . 25 3993 - 4004 . DOI: 10.1002/chem.201804383 http://doi.org/10.1002/chem.201804383 .
Poursalehia, Z.; Salehib, R.; Samadic, N.; Rastad, H. S.; Mansoorie, B. . A simple strategy for chemo-photothermal ablation of breast cancer cells by novel smart gold nanoparticles . Photodiagn. Photodyn. , 2019 . 28 25 - 37 . .
Oluwole, D. O.; Manotob, S. L.; Malabib, R.; Maphangab, C. . Evaluation of the photophysicochemical properties and photodynamic therapy activity of nanoconjugates of zinc phthalocyanine linked to glutathione capped Au and Au 3 Ag 1 nanoparticles . Dyes Pigments , 2018 . 150 139 - 150 . DOI: 10.1016/j.dyepig.2017.11.019 http://doi.org/10.1016/j.dyepig.2017.11.019 .
Lopatynsky, A. M.; Malymon, Y. O.; Lytvyn, V. K.; Mogylnyi, I. V.; Rachkov, A. E. . Solid and hollow gold nanostructures for nanomedicine: comparison of photothermal properties . Plasmonics. , 2018 . 13 1659 - 1669 . DOI: 10.1007/s11468-017-0675-1 http://doi.org/10.1007/s11468-017-0675-1 .
Rozanova, N.; Zhang, J. Z. . Photothermal ablation therapy for cancer based on metal nanostructures . Sci. China B , 2009 . 10 1559 - 1575 . .
Gong, X.; Tong, M.; Xia, Y.; Cai, W.; Moon, J. S.; Cao, Y. . High-Detectivity polymer photodetectors with spectral response from 300 nm to 1450 nm . Science , 2009 . 325 1665 - 1667 . DOI: 10.1126/science.1176706 http://doi.org/10.1126/science.1176706 .
Yang, J.; Cai, Y.; Zhou, Y. X.; Zhang, C. X.; Liang, P. P.; Zhao, B. M.; Shao, J. J.; Fu, N. N.; Huang, W.; Dong, X. C. . Highly effective thieno[2,3- b ]indole-diketopyrrolopyrrole near-infrared photosensitizer for photodynamic/photothermal dual mode therapy . Dyes Pigments. , 2017 . 147 270 - 282 . DOI: 10.1016/j.dyepig.2017.08.023 http://doi.org/10.1016/j.dyepig.2017.08.023 .
Cai, Y.; Tang, Q. Y.; Wu, X. J.; Si, W. L.; Huang, W. . Diketopyrrolopyrrole derivatives grafting hyaluronic acid for targeted photodynamic therapy . Chemistry Select. , 2016 . 1 3071 - 3074 . .
Wang, W.; Zhang, F.; Bai, H.; Li, L.; Gao, M.; Zhang, M. . Photomultiplication photodetectors with P3HT: fullerene-free material as the active layers exhibiting a broad response . Nanoscale , 2016 . 8 5578 - 5586 . DOI: 10.1039/C6NR00079G http://doi.org/10.1039/C6NR00079G .
Qi, J.; Zhou, X. K.; Yang, D. Z.; Qiao, W. Q.; Wang, Z. Y. . Optimization of solubility, film morphology and photodetector performance by molecular side-chain engineering of low-bandgap thienothiadiazole-based polymers . Adv. Funct. Mater. , 2014 . 24 7605 - 7612 . DOI: 10.1002/adfm.201401948 http://doi.org/10.1002/adfm.201401948 .
Lyu, Y.; Fang, Y.; Miao, Q.; Zhen, X.; Ding, D.; Pu, K. . Intraparticle molecular orbital engineering of semiconducting polymer nanoparticles as amplified theranostics for in vivo photoacoustic imaging and photothermal therapy . ACS Nano , 2016 . 10 4472 - 4481 . DOI: 10.1021/acsnano.6b00168 http://doi.org/10.1021/acsnano.6b00168 .
Dong, R.; Bi, C.; Dong, Q. F.; Guo, F. W.; Yuan, Y. B.; Fang, Y. J.; Xiao, Z. G.; Huang, J. S. . An ultraviolet-to-NIR broad spectral nanocomposite photodetector with gain . Adv. Opt. Mater. , 2014 . 2 549 - 554 . DOI: 10.1002/adom.201400023 http://doi.org/10.1002/adom.201400023 .
Hendriks., K. H.; Heintges G. H. L.; Gevaerts, V. S.; Wienk, M. M.; Janssen, R. A. J. . High-molecular-weight regular alternating diketopyrrolopyrrole-based terpolymers for efficient organic solar cells . Angew. Chem. Int. Ed. , 2013 . 52 8341 - 8344 . DOI: 10.1002/anie.201302319 http://doi.org/10.1002/anie.201302319 .
Li, W. T.; Wang, L. Y.; Tang, H. . Diketopyrrolopyrrole-based fluorescent probes for detection and bioimaging: current progresses and perspectives . Dyes Pigments , 2019 . 162 934 - 950 . DOI: 10.1016/j.dyepig.2018.11.023 http://doi.org/10.1016/j.dyepig.2018.11.023 .
Roper, D. K.; Ahn, W.; Hoepfner, M. . Microscale heat transfer transduced by surface plasmonresonant gold nanoparticles . J. Phys. Chem. C , 2007 . 111 3636 - 3641 . DOI: 10.1021/jp064341w http://doi.org/10.1021/jp064341w .
Hessel, C. M.; Pattani, V. P.; Rasch, M.; Panthani, M. G. . Copper selenide nanocrystals for photothermal therapy . Nano Lett. , 2011 . 11 2560 - 2566 . DOI: 10.1021/nl201400z http://doi.org/10.1021/nl201400z .
Liu, Y. L.; Ai, K. L.; Liu, J. H.; Deng, M.; He, Y. Y.; Lu, L. H. . Dopamine-melanin colloidal nanospheres: an efficient near-infrared photothermal therapeutic agent for in vivo cancer therapy . Adv. Mater. , 2013 . 25 1353 - 1359 . DOI: 10.1002/adma.201204683 http://doi.org/10.1002/adma.201204683 .
Zhang, W.; Lin, W. H.; Wang, X.; Li, C. N.; Liu, S.; Xie, Z. G. . Hybrid nanomaterials of conjugated polymers and albumin for precise photothermal therapy . ACS Appl. Mater. Interfaces , 2019 . 11 278 - 287 . DOI: 10.1021/acsami.8b17922 http://doi.org/10.1021/acsami.8b17922 .
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