

FOLLOWUS
a.Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education, School of Chemistry, Beihang University, Beijing 100191, China
b.International Research Institute for Multidisciplinary Science, Beihang University, Beijing 100191, China
c.Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, China
Ming-Jie Liu, E-mail liumj@buaa.edu.cn
Received:22 November 2017,
Accepted:22 December 2017,
Online First:08 February 2018,
Published:2018-06
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Zi-Guang Zhao, Yi-Chao Xu, Ruo-Chen Fang, et al. Bioinspired Adaptive Gel Materials with Synergistic Heterostructures[J]. Chinese Journal of Polymer Science, 2018, 36(6): 683-696.
Zi-Guang Zhao, Yi-Chao Xu, Ruo-Chen Fang, et al. Bioinspired Adaptive Gel Materials with Synergistic Heterostructures[J]. Chinese Journal of Polymer Science, 2018, 36(6): 683-696. DOI: 10.1007/s10118-018-2105-z.
In nature
many biological soft tissues with synergistic heterostructures
such as sea cucumbers
skeletal muscles and cartilages
exhibit high functionality to adapt to complex environments. In artificial soft materials
hydrogels are similar to biological soft tissues due to the unique integration of "soft and wet" properties and elastic characteristics. However
currently hydrogel materials lack their necessary adaptability
including narrow working temperature windows and uncontrollable mechanics
thus restrict their engineering application in complex environments. Inspired by abovementioned biological soft tissues
researchers have increasingly developed heterostructural gel materials as functional soft materials with high adaptability to various mechanical and environmental conditions. This article summarizes our recent work on high-performance adaptive gel materials with synergistic heterostructures
including the critical design criteria and the state-of-the-art fabrication strategies of our gel materials. The functional adaptation properties of these heterostructural gel materials are also presented in details
including temperature
wettability
mechanical and shape adaption.
Z. Zhao , R. Fang , Q. Rong , M. Liu . Bioinspired nanocomposite hydrogels with highly ordered structures . Adv. Mater. , 2017 . 29 ( 45 ): DOI: 10.1002/adma.201703045 http://doi.org/10.1002/adma.201703045 .
B. V. Slaughter , S. S. Khurshid , O. Z. Fisher , A. Khademhosseini , N. A. Peppas . Hydrogels in regenerative medicine . Adv. Mater. , 2009 . 21 ( 32 ): 3307 - 3329 . http://www.ncbi.nlm.nih.gov/pubmed/20882499 http://www.ncbi.nlm.nih.gov/pubmed/20882499 , .
M. Liu , S. Wang , L. Jiang . Nature-inspired superwettability systems . Nat. Rev. Mater. , 2017 . 2 17036 DOI: 10.1038/natrevmats.2017.36 http://doi.org/10.1038/natrevmats.2017.36 .
L. Chen , Y. Yin , Y. Liu , L. Lin , M. Liu . Design and fabrication of functional hydrogels through interfacial engineering . Chinese J. Polym. Sci. , 2017 . 35 ( 10 ): 1181 - 1193 . DOI: 10.1007/s10118-017-1995-5 http://doi.org/10.1007/s10118-017-1995-5 .
K. Y. Lee , D. J. Mooney . Hydrogels for tissue engineering . Chem. Rev. , 2001 . 101 ( 7 ): 1869 - 1880 . DOI: 10.1021/cr000108x http://doi.org/10.1021/cr000108x .
D. L. Taylor , M. Panhuis . Self-healing hydrogels . Adv. Mater. , 2016 . 28 ( 41 ): 9060 - 9093 . DOI: 10.1002/adma.201601613 http://doi.org/10.1002/adma.201601613 .
H. Yuk , S. Lin , C. Ma , M. Takaffoli , N. X. Fang , X. Zhao . Hydraulic hydrogel actuators and robots optically and sonically camouflaged in water . Nat. Commun. , 2017 . 8 DOI: 10.1038/ncomms14230 http://doi.org/10.1038/ncomms14230 .
B. P. Lee , S. Konst . Novel hydrogel actuator inspired by reversible mussel adhesive protein chemistry . Adv. Mater. , 2014 . 26 ( 21 ): 3415 - 3419 . DOI: 10.1002/adma.v26.21 http://doi.org/10.1002/adma.v26.21 .
M. K. Shin , G. M. Spinks , S. R. Shin , S. I. Kim , S. J. Kim . Nanocomposite hydrogel with high toughness for bioactuators . Adv. Mater. , 2009 . 21 ( 17 ): 1712 - 1715 . DOI: 10.1002/adma.v21:17 http://doi.org/10.1002/adma.v21:17 .
S. R. Shin , S. M. Jung , M. Zalabany , K. Kim , P. Zorlutuna , S. B. Kim , M. Nikkhah , M. Khabiry , M. Azize , J. Kong , K. T. Wan , T. Palacios , M. R. Dokmeci , H. Bae , X. Tang , A. Khademhosseini . Carbon-nanotube-embedded hydrogel sheets for engineering cardiac constructs and bioactuators . ACS Nano , 2013 . 7 ( 3 ): 2369 - 2380 . DOI: 10.1021/nn305559j http://doi.org/10.1021/nn305559j .
H. R. Culver , J. R. Clegg , N. A. Peppas . Analyte-responsive hydrogels:intelligent materials for biosensing and drug delivery . Acc. Chem. Res. , 2017 . 50 ( 2 ): 170 - 178 . DOI: 10.1021/acs.accounts.6b00533 http://doi.org/10.1021/acs.accounts.6b00533 .
J. F. Xing , M. L. Zheng , X. M. Duan . Two-photon polymerization microfabrication of hydrogels:an advanced 3D printing technology for tissue engineering and drug delivery . Chem. Soc. Rev. , 2015 . 44 5031 - 5039 . DOI: 10.1039/C5CS00278H http://doi.org/10.1039/C5CS00278H .
P. Wang , J. Sun , Z. Lou , F. Fan , K. Hu , Y. Sun , N. Gu . Assembly-induced thermogenesis of gold nanoparticles in the presence of alternating magnetic field for controllable drug release of hydrogel . Adv. Mater. , 2016 . 28 ( 48 ): 10801 - 10808 . DOI: 10.1002/adma.201603632 http://doi.org/10.1002/adma.201603632 .
J. Liu , C. S. Tan , Z. Yu , Y. Lan , C. Abell , O. A. Scherman . Biomimetic supramolecular polymer networks exhibiting both toughness and self-recovery . Adv. Mater. , 2017 . 29 ( 10 ): DOI: 10.1002/adma.201604951 http://doi.org/10.1002/adma.201604951 .
Z. Liu , P. Calvert . Multilayer hydrogels as muscle-like actuators . Adv. Mater. , 2000 . 12 ( 4 ): 288 - 291 . DOI: 10.1002/(ISSN)1521-4095 http://doi.org/10.1002/(ISSN)1521-4095 .
J. M. VanBemmelen . Der hydrogel und das kristallinische hydrat des kupferoxydes . Z. Anorg. Chem. , 1894 . 5 466 - 483 . DOI: 10.1002/(ISSN)1521-3749 http://doi.org/10.1002/(ISSN)1521-3749 .
O. Wichterle , D. Lím . Hydrophilic gels for biological use . Nature , 1960 . 185 117 - 118 . DOI: 10.1038/185117a0 http://doi.org/10.1038/185117a0 .
J. Jokl , J. Kopeček , D. Lím . Mechanism of three-dimensional polymerization of the system methyl methacrylate-glycol dimethacrylate.Ⅰ. Determination of the structure of the threedimensional product . J. Polym. Sci. A1 Polym. Chem. , 1968 . 6 ( 11 ): 3041 - 3048 . DOI: 10.1002/pol.1968.150061108 http://doi.org/10.1002/pol.1968.150061108 .
M. F. Refojo , H. Yasuda . Hydrogels from 2-hydroxyethyl methacrylate and propylene glycol monoacrylate . J. Appl. Polym. Sci. , 1965 . 9 ( 7 ): 2425 - 2435 . DOI: 10.1002/app.1965.070090707 http://doi.org/10.1002/app.1965.070090707 .
G. P. Hicks , S. J. Updike . The preparation and characterization of lyophilized polyacrylamide enzyme gels for chemical analysis . Anal. Chem. , 1966 . 38 ( 6 ): 726 - 730 . DOI: 10.1021/ac60238a014 http://doi.org/10.1021/ac60238a014 .
A. Freeman , Y. Aharonowitz . Immobilization of microbial cells in crosslinked, prepolymerized, linear polyacrylamide gels:antibiotic production by immobilized Streptomyces clavuligerus cells . Biotechnol. Bioeng. , 1981 . 23 ( 12 ): 2747 - 2759 . DOI: 10.1002/(ISSN)1097-0290 http://doi.org/10.1002/(ISSN)1097-0290 .
K. Otake , H. Inomata , M. Konno , S. Saito . Thermal analysis of the volume phase transition with N -isopropylacrylamide gels . Macromolecules , 1990 . 23 ( 1 ): 283 - 289 . DOI: 10.1021/ma00203a049 http://doi.org/10.1021/ma00203a049 .
H. Inomata , S. Goto , S. Saito . Phase transition of N -substituted acrylamide gels . Macromolecules , 1990 . 23 ( 22 ): 4887 - 4888 . DOI: 10.1021/ma00224a023 http://doi.org/10.1021/ma00224a023 .
L. C. Dong , Y. Qi , A. S. Hoffman . Controlled release of amylase from a thermal and pH-sensitive, macroporous hydrogel . J. Control. Release , 1992 . 19 ( 1 ): 171 - 177 . http://www.sciencedirect.com/science/article/pii/0168365992900742 http://www.sciencedirect.com/science/article/pii/0168365992900742 , .
X. Zhao . Multi-scale multi-mechanism design of tough hydrogels:building dissipation into stretchy networks . Soft Matter , 2014 . 10 672 - 687 . DOI: 10.1039/C3SM52272E http://doi.org/10.1039/C3SM52272E .
K. Haraguchi , T. Takehisa , M. Ebato . Control of cell cultivation and cell sheet detachment on the surface of polymer/clay nanocomposite hydrogels . Biomacromolecules , 2006 . 7 ( 11 ): 3267 - 3275 . DOI: 10.1021/bm060549b http://doi.org/10.1021/bm060549b .
K. Haraguchi , H. J. Li . Control of the coil-to-globule transition and ultrahigh mechanical properties of PNIPA in nanocomposite hydrogels . Angew. Chem. Int. Ed. , 2005 . 44 ( 40 ): 6500 - 6504 . DOI: 10.1002/(ISSN)1521-3773 http://doi.org/10.1002/(ISSN)1521-3773 .
J. P. Gong , Y. Katsuyama , T. Kurokawa , Y. Osada . Doublenetwork hydrogels with extremely high mechanical strength . Adv. Mater. , 2003 . 15 ( 14 ): 1155 - 1158 . DOI: 10.1002/adma.200304907 http://doi.org/10.1002/adma.200304907 .
J. Y. Sun , X. Zhao , W. R. Illeperuma , O. Chaudhuri , K. H. Oh , D. J. Mooney , J. J. Vlassak , Z. Suo . Highly stretchable and tough hydrogels . Nature , 2012 . 489 133 - 136 . DOI: 10.1038/nature11409 http://doi.org/10.1038/nature11409 .
N. Rauner , M. Meuris , M. Zoric , J. C. Tiller . Enzymatic mineralization generates ultrastiff and tough hydrogels with tunable mechanics . Nature , 2017 . 543 407 - 410 . DOI: 10.1038/nature21392 http://doi.org/10.1038/nature21392 .
Q. Wang , J. L. Mynar , M. Yoshida , E. Lee , M. Lee , K. Okuro , K. Kinbara , T. Aida . High-water-content mouldable hydrogels by mixing clay and a dendritic molecular binder . Nature , 2010 . 463 339 - 343 . DOI: 10.1038/nature08693 http://doi.org/10.1038/nature08693 .
H. Kamata , Y. Akagi , Y. Kayasuga-Kariya , U. I. Chung , T. Sakai . "Nonswellable" hydrogel without mechanical hysteresis . Science , 2014 . 343 ( 6173 ): 873 - 875 . DOI: 10.1126/science.1247811 http://doi.org/10.1126/science.1247811 .
M. Liu , Y. Ishida , Y. Ebina , T. Sasaki , T. Hikima , M. Takata , T. Aida . An anisotropic hydrogel with electrostatic repulsion between cofacially aligned nanosheets . Nature , 2015 . 517 68 - 72 . DOI: 10.1038/nature14060 http://doi.org/10.1038/nature14060 .
H. N. Kim , A. Jiao , N. S. Hwang , M. S. Kim , D. H. Kang , D. H. Kim , K. Y. Suh . Nanotopography-guided tissue engineering and regenerative medicine . Adv. Drug. Delivery Rev. , 2013 . 65 ( 4 ): 536 - 558 . DOI: 10.1016/j.addr.2012.07.014 http://doi.org/10.1016/j.addr.2012.07.014 .
M. Liu , L. Jiang . Dialectics of nature in materials science:binary cooperative complementary materials . Sci. China Mater. , 2016 . 59 ( 4 ): 239 - 246 . DOI: 10.1007/s40843-016-5051-6 http://doi.org/10.1007/s40843-016-5051-6 .
N. Oliva , J. Conde , K. Wang , N. Artzi . Designing hydrogels for on-demand therapy . Acc. Chem. Res. , 2017 . 50 ( 4 ): 669 - 679 . DOI: 10.1021/acs.accounts.6b00536 http://doi.org/10.1021/acs.accounts.6b00536 .
X. Q. Dou , C. L. Feng . Amino acids and peptide-based supramolecular hydrogels for three-dimensional cell culture . Adv. Mater. , 2017 . 29 ( 16 ): 1604062 DOI: 10.1002/adma.201604062 http://doi.org/10.1002/adma.201604062 .
U. G. Wegst , H. Bai , E. Saiz , A. P. Tomsia , R. O. Ritchie . Bioinspired structural materials . Nat. Mater. , 2015 . 14 23 - 36 . DOI: 10.1038/nmat4089 http://doi.org/10.1038/nmat4089 .
T. Motokawa . Effects of ionic environment on viscosity of Triton-extracted catch connective tissue of a sea cucumber body wall . Comp. Biochem. Physiol. Part B , 1994 . 109 ( 4 ): 613 - 622 . DOI: 10.1016/0305-0491(94)90124-4 http://doi.org/10.1016/0305-0491(94)90124-4 .
F. A. Thurmond , J. A. Trotter . Morphology and biomechanics of the microfibrillar network of sea cucumber dermis . J. Exp. Biol. , 1996 . 199 1817 - 1828 . http://www.ncbi.nlm.nih.gov/pubmed/9319729 http://www.ncbi.nlm.nih.gov/pubmed/9319729 , .
G. K. Szulgit , R. E. Shadwick . Dynamic mechanical characterization of a mutable collagenous tissue:response of sea cucumber dermis to cell lysis and dermal extracts . J. Exp. Biol. , 2000 . 203 ( 10 ): 1539 - 1550 . http://www.ncbi.nlm.nih.gov/pubmed/10769216 http://www.ncbi.nlm.nih.gov/pubmed/10769216 , .
J. R. Capadona , K. Shanmuganathan , D. J. Tyler , S. J. Rowan , C. Weder . Stimuli-responsive polymer nanocomposites inspired by the sea cucumber dermis . Science , 2008 . 319 ( 5868 ): 1370 - 1374 . DOI: 10.1126/science.1153307 http://doi.org/10.1126/science.1153307 .
J. Mo , S. F. Prévost , L. M. Blowes , M. Egertová , N. J. Terrill , W. Wang , M. R. Elphick , H. S. Gupta . Interfibrillar stiffening of echinoderm mutable collagenous tissue demonstrated at the nanoscale . P. Natl. Acad. Sci. USA , 2016 . 113 ( 42 ): E6362 - E6371 . DOI: 10.1073/pnas.1609341113 http://doi.org/10.1073/pnas.1609341113 .
M. A. Johnson , J. Polgar , D. Weightman , D. Appleton . Data on the distribution of fibre types in thirty-six human muscles:an autopsy study . J. Neurol. Sci. , 1973 . 18 ( 1 ): 111 - 129 . DOI: 10.1016/0022-510X(73)90023-3 http://doi.org/10.1016/0022-510X(73)90023-3 .
Tiidus, P. M., "Skeletal muscle damage and repair", Human Kinetics Press, Champaign, IL USA, 2008, p. 37
M. J. Wakelam . The fusion of myoblasts . Biochem. J. , 1985 . 228 1 - 12 . DOI: 10.1042/bj2280001 http://doi.org/10.1042/bj2280001 .
P. M. Wigmore , G. F. Dunglison . The generation of fiber diversity during myogenesis . Int. J. Dev. Biol. , 1998 . 42 ( 2 ): 117 - 125 . .
S. Jana , S. K. Levengood , M. Zhang . Anisotropic materials for skeletal-muscle-tissue engineering . Adv. Mater. , 2016 . 28 ( 48 ): 10588 - 10612 . DOI: 10.1002/adma.201600240 http://doi.org/10.1002/adma.201600240 .
A. J. Kerin , M. R. Wisnom , M. A. Adams . The compressive strength of articular cartilage . Proc. Inst. Mech. Eng. Part H , 1998 . 212 ( 4 ): 273 - 280 . DOI: 10.1243/0954411981534051 http://doi.org/10.1243/0954411981534051 .
S. Tepic , T. Macirowski , R. W. Mann . Mechanical properties of articular cartilage elucidated by osmotic loading and ultrasound . Proc. Natl. Acad. Sci. USA , 1983 . 80 ( 11 ): 3331 - 3333 . DOI: 10.1073/pnas.80.11.3331 http://doi.org/10.1073/pnas.80.11.3331 .
P. Fratzl , R. Weinkamer . Nature's hierarchical materials . Prog. Mater. Sci. , 2007 . 52 ( 8 ): 1263 - 1334 . DOI: 10.1016/j.pmatsci.2007.06.001 http://doi.org/10.1016/j.pmatsci.2007.06.001 .
N. K. Simha , C. S. Carlson , J. L. Lewis . Evaluation of fracture toughness of cartilage by micropenetration . J. Mater. Sci. Mater. Med. , 2004 . 15 ( 5 ): 631 - 639 . DOI: 10.1023/B:JMSM.0000026104.30607.c7 http://doi.org/10.1023/B:JMSM.0000026104.30607.c7 .
R. F. Ker . The design of soft collagenous load-bearing tissues . J. Exp. Biol. , 1999 . 202 ( 23 ): 3315 - 3324 . http://www.ncbi.nlm.nih.gov/pubmed/10562514 http://www.ncbi.nlm.nih.gov/pubmed/10562514 , .
G. Bellucci , B. B. Seedhom . Mechanical behaviour of articular cartilage under tensile cyclic load . Rheumatology , 2001 . 40 ( 12 ): 1337 - 1345 . DOI: 10.1093/rheumatology/40.12.1337 http://doi.org/10.1093/rheumatology/40.12.1337 .
R. W. Salt . Survival of frozen fat body cells in an insect . Nature , 1959 . 184 1426 - 1426 . https://www.nature.com/articles/1841426a0 https://www.nature.com/articles/1841426a0 , .
M. F. Thomashow . Plant cold acclimation:freezing tolerance genes and regulatory mechanisms . Annu. Rev. Plant Physiol. Plant Mol. Biol. , 1999 . 50 571 - 599 . DOI: 10.1146/annurev.arplant.50.1.571 http://doi.org/10.1146/annurev.arplant.50.1.571 .
E. R. Moellering , B. Muthan , C. Benning . Freezing tolerance in plants requires lipid remodeling at the outer chloroplast membrane . Science , 2010 . 330 ( 6001 ): 226 - 228 . DOI: 10.1126/science.1191803 http://doi.org/10.1126/science.1191803 .
D. Takahashi , H. Imai , Y. Kawamura , M. Uemura . Lipid profiles of detergent resistant fractions of the plasma membrane in oat and rye in association with cold acclimation and freezing tolerance . Cryobiology , 2016 . 72 ( 2 ): 123 - 134 . DOI: 10.1016/j.cryobiol.2016.02.003 http://doi.org/10.1016/j.cryobiol.2016.02.003 .
F. Martz , M. L. Sutinen , S. Kiviniemi , J. P. Palta . Changes in freezing tolerance, plasma membrane H+-ATPase activity and fatty acid composition in Pinus resinosa needles during cold acclimation and de-acclimatio . Tree Physiol. , 2006 . 26 ( 6 ): 783 - 790 . DOI: 10.1093/treephys/26.6.783 http://doi.org/10.1093/treephys/26.6.783 .
H. Gao , Z. Zhao , Y. Cai , J. Zhou , W. Hua , L. Chen , L. Wang , J. Zhang , D. Han , M. Liu , L. Jiang . Adaptive and freezetolerant heteronetwork organohydrogels with enhanced mechanical stability over a wide temperature range . Nat. Commun. , 2017 . 8 DOI: 10.1038/ncomms15911 http://doi.org/10.1038/ncomms15911 .
Q. Rong , W. Lei , L. Chen , Y. Yin , J. Zhou , M. Liu . Antifreezing, conductive self-healing organohydrogels with stable strain-sensitivity at subzero temperatures . Angew. Chem. Int. Ed. , 2017 . 129 ( 45 ): 14347 - 14351 . DOI: 10.1002/ange.201708614 http://doi.org/10.1002/ange.201708614 .
S. Shi , X. Peng , T. Liu , Y. N. Chen , C. He , H. Wang . Facile preparation of hydrogen-bonded supramolecular polyvinyl alcohol-glycerol gels with excellent thermoplasticity and mechanical properties . Polymer , 2017 . 111 ( 24 ): 168 - 176 . https://www.sciencedirect.com/science/article/pii/S0032386117300770?via%3Dihub https://www.sciencedirect.com/science/article/pii/S0032386117300770?via%3Dihub , .
J. Shin , J. S. Lee , C. Lee , H. J. Park , K. Yang , Y. Jin , J. H. Ryu , K. S. Hong , S. H. Moon , H. M. Chung , H. S. Yang , S. H. Um , J. W. Oh , D. I. Kim , H. Lee , S. W. Cho . Tissue adhesive catechol-modified hyaluronic acid hydrogel for effective, minimally invasive cell therapy . Adv. Funct. Mater. , 2015 . 25 ( 25 ): 3814 - 3824 . DOI: 10.1002/adfm.v25.25 http://doi.org/10.1002/adfm.v25.25 .
Y. Liu , H. Meng , S. Konst , R. Sarmiento , R. Rajachar , B. P. Lee . Injectable dopamine-modified poly(ethylene glycol) nanocomposite hydrogel with enhanced adhesive property and bioactivity . ACS Appl. Mater. Interfaces , 2014 . 6 ( 19 ): 16982 - 16992 . DOI: 10.1021/am504566v http://doi.org/10.1021/am504566v .
Y. B. Lee , Y. M. Shin , E. M. Kim , J. Lim , J. Y. Lee , H. Shin . Facile cell sheet harvest and translocation mediated by a thermally expandable hydrogel with controlled cell adhesion . Adv. Healthc. Mater. , 2016 . 5 ( 18 ): 2320 - 2324 . DOI: 10.1002/adhm.v5.18 http://doi.org/10.1002/adhm.v5.18 .
D. J. Thornton , J. K. Sheehan . From mucins to mucus:toward a more coherent understanding of this essential barrier . Proc. Am. Thorac. Soc. , 2004 . 1 ( 1 ): 54 - 61 . DOI: 10.1513/pats.2306016 http://doi.org/10.1513/pats.2306016 .
K. Weis . The nuclear pore complex:oily spaghetti or gummy bear? . Cell , 2007 . 130 ( 3 ): 405 - 407 . DOI: 10.1016/j.cell.2007.07.029 http://doi.org/10.1016/j.cell.2007.07.029 .
X. Yao , L. Chen , J. Ju , C. Li , Y. Tian , L. Jiang , M. Liu . Superhydrophobic diffusion barriers for hydrogels via confined interfacial modification . Adv. Mater. , 2016 . 28 ( 34 ): 7383 - 7389 . DOI: 10.1002/adma.201601568 http://doi.org/10.1002/adma.201601568 .
L. Chen , X. Yao , Z. Gu , K. Zheng , C. Zhao , W. Lei , Q. Rong , L. Lin , J. Wang , L. Jiang , M. Liu . Covalent tethering of photo-responsive superficial layers on hydrogel surfaces for photo-controlled release . Chem. Sci. , 2017 . 8 2010 - 2016 . DOI: 10.1039/C6SC04634G http://doi.org/10.1039/C6SC04634G .
H. Chen , F. Y. Yang , Q. Chen , J. Zheng . A novel design of multi-mechanoresponsive and mechanically strong hydrogels . Adv. Mater. , 2017 . 29 ( 21 ): DOI: 10.1002/adma.201606900 http://doi.org/10.1002/adma.201606900 .
C. Bilici , V. Can , U. Nçchel , M. Behl , A. Lendlein , O. Okay . Melt-processable shape-memory hydrogels with self-healing ability of high mechanical strength . Macromolecules , 2016 . 49 ( 19 ): 7442 - 7449 . DOI: 10.1021/acs.macromol.6b01539 http://doi.org/10.1021/acs.macromol.6b01539 .
R. C. Luo , J. Wu , N. D. Dinh , C. H. Chen . Gradient porous elastic hydrogels with shape-memory property and anisotropic responses for programmable locomotion . Adv. Funct. Mater. , 2015 . 25 ( 47 ): 7272 - 7279 . DOI: 10.1002/adfm.v25.47 http://doi.org/10.1002/adfm.v25.47 .
W. Wang , Y. Y. Zhang , W. G. Liu . Bioinspired fabrication of high strength hydrogels from non-covalent interactions . Prog. Polym. Sci. , 2017 . 71 1 - 25 . DOI: 10.1016/j.progpolymsci.2017.04.001 http://doi.org/10.1016/j.progpolymsci.2017.04.001 .
X. Y. Dai , Y. Y. Zhang , L. N. Gao , T. Bai , W. Wang , Y. L. Cui , W. G. Liu . A mechanically strong, highly stable, thermoplastic, and self-healable supramolecular polymer hydrogel . Adv. Mater. , 2015 . 27 ( 23 ): 3566 - 3571 . DOI: 10.1002/adma.v27.23 http://doi.org/10.1002/adma.v27.23 .
C. H. Lu , W. Guo , Y. Hu , X. J. Qi , I. Willner . Multitriggered shape-memory acrylamide-DNA hydrogels . J. Am. Chem. Soc. , 2015 . 137 ( 50 ): 15723 - 15731 . DOI: 10.1021/jacs.5b06510 http://doi.org/10.1021/jacs.5b06510 .
Z. Zhao , K. Zhang , Y. Liu , J. Zhou , M. Liu . Highly stretchable, shape memory organohydrogels using phasetransition microinclusions . Adv. Mater. , 2017 . 29 ( 33 ): 1701695 DOI: 10.1002/adma.v29.33 http://doi.org/10.1002/adma.v29.33 .
Z. Zhao , Y. Liu , K. Zhang , S. Zhuo , R. Fang , J. Zhang , L. Jiang , M. Liu . Biphasic synergistic gel materials with switchable mechanics and self-healing capacity . Angew. Chem. Int. Ed. , 2017 . 129 ( 43 ): 13649 - 13654 . DOI: 10.1002/ange.201707239 http://doi.org/10.1002/ange.201707239 .
Y. S. Kim , M. Liu , Y. Ishida , Y. Ebina , M. Osada , T. Sasaki , T. Hikima , M. Takata , T. Aida . Thermoresponsive actuation enabled by permittivity switching in an electrostatically anisotropic hydrogel . Nat. Mater. , 2015 . 14 1002 - 1007 . DOI: 10.1038/nmat4363 http://doi.org/10.1038/nmat4363 .
M. Liu , Y. Ishida , Y. Ebina , T. Sasaki , T. Aida . Photolatently modulable hydrogels using unilamellar titania nanosheets as photocatalytic crosslinkers . Nat. Commun. , 2013 . 4 2029 DOI: 10.1038/ncomms3029 http://doi.org/10.1038/ncomms3029 .
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