Controlled Cross-linking Strategy for Formation of Hydrogels, Microgels and Nanogels

Qing-Chen Cao; Xing Wang; De-Cheng Wu

doi:10.1007/s10118-018-2061-7

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Controlled Cross-linking Strategy for Formation of Hydrogels, Microgels and Nanogels

Feature Articles | Updated：2021-02-18

- Controlled Cross-linking Strategy for Formation of Hydrogels, Microgels and Nanogels
- Chinese Journal of Polymer Science Vol. 36, Issue 1, Pages: 8-17(2018)
- Affiliations：
  
  a.Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
  b.University of Chinese Academy of Sciences, Beijing 100049, China
- Author bio：
  
  E-mail wangxing@iccas.ac.cn (X.W.)
  E-mail dcwu@iccas.ac.cn (D.C.W.)
- Funds：
- DOI：10.1007/s10118-018-2061-7
  CLC：
- Received：29 September 2017，
  
  Revised：2017-10-11，
  
  Accepted：11 October 2017，
  
  Online First：30 October 2017，
  
  Published：05 January 2018
- Accepted：
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Qing-Chen Cao, Xing Wang, De-Cheng Wu. Controlled Cross-linking Strategy for Formation of Hydrogels, Microgels and Nanogels[J]. Chinese Journal of Polymer Science, 2018, 36(1): 8-17.
DOI：

Qing-Chen Cao, Xing Wang, De-Cheng Wu. Controlled Cross-linking Strategy for Formation of Hydrogels, Microgels and Nanogels[J]. Chinese Journal of Polymer Science, 2018, 36(1): 8-17. DOI： 10.1007/s10118-018-2061-7.

摘要

Abstract

Hydrogels are a kind of unique cross-linking polymeric materials with three-dimensional networks. Various efforts have been devoted to manipulate the formation of functional hydrogels

in situ

and enrich the production of hydrogels

microgels and nanogels with improved modulation capacity. However

these methods always fail to tune the gel properties because of the difficulty in achieving the precise control of cross-linking extents once the gel formation is initiated. Therefore

the preparation of tailor-made hydrogels remains a great challenge. Herein

we summarize a controlled cross-linking strategy towards not only fabrication of hydrogels at nano-

micro-and macro-scales

but also achievement of controlled assembly of nanoparticles into multifunctional materials in macroscopic and microscopic scales. The strategy is conducted by controllably activating and terminating the disulfide reshuffling reactions of disulfide-linked core/shell materials with selective core/shell separation using system pH or UV triggers. So it provides a facile approach to producing hydrogels

hydrogel particles and nanoparticle aggregates with tunable structures and properties

opening up the design possibility

flexibility and complexity of hydrogels

microgels/nanogels and nanoparticle aggregates from nanoscopic components to macroscopic objects.

关键词

Keywords

references

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