Yan Zhang, Zi-Peng Yuan, Yu Qin, et al. Comparative Studies on Hydrophilic and Hydrophobic Segments Grafted Poly(vinyl chloride)[J]. Chinese Journal of Polymer Science, 2018, 36(5): 604-611.
DOI:
Yan Zhang, Zi-Peng Yuan, Yu Qin, et al. Comparative Studies on Hydrophilic and Hydrophobic Segments Grafted Poly(vinyl chloride)[J]. Chinese Journal of Polymer Science, 2018, 36(5): 604-611.DOI: 10.1007/s10118-018-2034-x.
Comparative Studies on Hydrophilic and Hydrophobic Segments Grafted Poly(vinyl chloride)
Poly(vinyl chloride) (PVC) is one of the mostly produced plastics in the world and is widely used in single-use medical devices. However
the additives that are often necessary for PVC arouse concerns of its safety
thus quests the modifications of PVC itself. In this study
poly(ethylene glycol) (PEG) and polydimethylsiloxane (PDMS) segments were grafted onto PVC backbone in similar ways
and the chemical structures of the modified PVCs were characterized by Fourier transform infrared spectra
X-ray photoelectron spectra
thermogravimetric analysis and differential scanning calorimetry. Moreover
the water contact angle
protein adsorption
platelet adhesion
cell attachment and proliferation on different material surfaces were studied and compared. It was found that both PEG and PDMS grafting yielded improvement on biocompatibility compared with bare PVC
while hydrophobic PDMS grafted PVC showed more effective on cell attachment and proliferation than that of hydrophilic PEG grafted PVC.
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Keywords
references
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