Tough Polyion Complex Hydrogel Films of Natural Polysaccharides

Feng-bo Zhu; Hai-chao Yu; Wen-xi Lei; Ke-feng Ren; Jin Qian; Zi-liang Wu; Qiang Zheng

doi:10.1007/s10118-017-1977-7

Your Location：

Home >

Browse articles >

Tough Polyion Complex Hydrogel Films of Natural Polysaccharides

Papers | Updated：2021-02-18

- Tough Polyion Complex Hydrogel Films of Natural Polysaccharides
- Chinese Journal of Polymer Science Vol. 35, Issue 10, Pages: 1276-1285(2017)
- Affiliations：
  
  a.Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
  b.Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province, Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, China
- Author bio：
  
  Zi-liang Wu (吴子良), E-mail:wuziliang@zju.edu.cn
- Funds：
- DOI：10.1007/s10118-017-1977-7
  CLC：
- Received：16 April 2017，
  
  Revised：2017-5-16，
  
  Accepted：17 May 2017，
  
  Published：05 October 2017
- Accepted：
Scan QR Code
Feng-bo Zhu, Hai-chao Yu, Wen-xi Lei, et al. Tough Polyion Complex Hydrogel Films of Natural Polysaccharides[J]. Chinese Journal of Polymer Science, 2017, 35(10): 1276-1285.
DOI：

Feng-bo Zhu, Hai-chao Yu, Wen-xi Lei, et al. Tough Polyion Complex Hydrogel Films of Natural Polysaccharides[J]. Chinese Journal of Polymer Science, 2017, 35(10): 1276-1285. DOI： 10.1007/s10118-017-1977-7.

摘要

Abstract

The developments of tough hydrogels in recent years have greatly expanded the applications of hydrogels as structural materials. However

most of the tough hydrogels are made of synthetic polymers. To develop biopolymer-based tough hydrogels has both fundamental and practical significances. Here we report a series of polysaccharides-based tough hydrogel films prepared by polyion complexation and solvent evaporation of chondroitin sulfate (CS) and protonated chitosan (CHT) solutions with different weight ratios. The obtained CS/CHT gel films with thickness of 40-80 μm and water content of 66 wt%-81 wt% possess excellent mechanical properties

with tensile breaking stress and breaking strain being 0.4-3 MPa and 160%-320%

respectively. We found that in the mixture solutions there are large amounts of excess CHT in terms of charges; after swelling the films in water

the acetic acid

which is used to protonate the amino groups of CHT

diffuses out of the gel matrix

enhancing the intermolecular interactions between CHT molecules and thus improving the mechanical properties of gel films

besides the ionic bonds between CS and CHT. Antimicrobial tests also showed that the gel films with low weight ratio of CS to CHT

corresponding to the case with excess CHT

have evident antimicrobial effect. These CS/CHT gel films with good mechanical properties and antimicrobial effect should extend the applications of hydrogels in biomedical fields.

关键词

Keywords

references

J.P. Gong , Y. Osada . Adv. Mater. , 1998 . 10 827 DOI: 10.1002/(ISSN)1521-4095 http://doi.org/10.1002/(ISSN)1521-4095 .

J.L. Drury , D.J. Mooney . Biomaterials , 2003 . 24 4337 DOI: 10.1016/S0142-9612(03)00340-5 http://doi.org/10.1016/S0142-9612(03)00340-5 .

Y. Qiu , K. Park . Adv. Drug Deliv. Rev. , 2001 . 53 321 DOI: 10.1016/S0169-409X(01)00203-4 http://doi.org/10.1016/S0169-409X(01)00203-4 .

L. Ionov . Adv. Funct. Mater. , 2013 . 23 4555 DOI: 10.1002/adfm.v23.36 http://doi.org/10.1002/adfm.v23.36 .

J.P. Gong . Soft Matter , 2010 . 6 2583 DOI: 10.1039/b924290b http://doi.org/10.1039/b924290b .

X. Zhao . Soft Matter , 2014 . 10 672 DOI: 10.1039/C3SM52272E http://doi.org/10.1039/C3SM52272E .

Y. Okumura , K. Ito . Adv. Mater. , 2001 . 13 485 DOI: 10.1002/(ISSN)1521-4095 http://doi.org/10.1002/(ISSN)1521-4095 .

K. Haraguchi , T. Takehisa . Adv. Mater. , 2002 . 14 1120 DOI: 10.1002/1521-4095(20020816)14:16<1120::AID-ADMA1120>3.0.CO;2-9 http://doi.org/10.1002/1521-4095(20020816)14:16<1120::AID-ADMA1120>3.0.CO;2-9 .

J.P. Gong , Y. Katsuyama , T. Kurokawa , Y. Osada . Adv. Mater. , 2003 . 15 1155 DOI: 10.1002/adma.200304907 http://doi.org/10.1002/adma.200304907 .

T. Huang , H. Xu , K. Jiao , L. Zhu , H.R. Brown , H. Wang . Adv. Mater. , 2007 . 19 1622 DOI: 10.1002/(ISSN)1521-4095 http://doi.org/10.1002/(ISSN)1521-4095 .

T. Sakai , T. Matsunaga , Y. Yamamoto , R. Yoshida , S. Suzuki , N. Sasaki , M. Shibayama , U.I. Chung . Macromolecules , 2008 . 41 5379 DOI: 10.1021/ma800476x http://doi.org/10.1021/ma800476x .

Q. Chen , L. Zhu , C. Zhao , Q. Wang , J. Zheng . Adv. Mater. , 2013 . 25 4171 DOI: 10.1002/adma.201300817 http://doi.org/10.1002/adma.201300817 .

J.Y. Sun , X. Zhao , W.R.K. Illeperuma , O. Chaudhuri , K.H. Oh , D.J. Mooney , J.J. Vlassak , Z. Suo . Nature , 2012 . 489 133 DOI: 10.1038/nature11409 http://doi.org/10.1038/nature11409 .

G. Du , F. Wu , Y. Cong , L. Nie , S. Liu , G. Gao , J. Fu . Chem. Commun. , 2015 . 51 15534 DOI: 10.1039/C5CC06721A http://doi.org/10.1039/C5CC06721A .

P. Lin , S. Ma , X. Wang , F. Zhou . Adv. Mater. , 2015 . 27 2054 DOI: 10.1002/adma.v27.12 http://doi.org/10.1002/adma.v27.12 .

X. Hu , M. Vatankhah-Varnoosfaderani , J. Zhou , Q. Li , S.S. Sheiko . Adv. Mater. , 2015 . 27 6899 DOI: 10.1002/adma.201503724 http://doi.org/10.1002/adma.201503724 .

X. Dai , Y. Zhang , L. Gao , T. Bai , W. Wang , Y. Cui , W. Liu . Adv. Mater. , 2015 . 27 3566 DOI: 10.1002/adma.v27.23 http://doi.org/10.1002/adma.v27.23 .

T.L. Sun , T. Kurokawa , S. Kuroda , A.B. Ihsan , T. Akasaki , K. Sato , M.A. Haque , T. Nakajima , J.P. Gong . Nat. Mater. , 2013 . 12 932 DOI: 10.1038/nmat3713 http://doi.org/10.1038/nmat3713 .

F. Luo , T.L. Sun , T. Nakajima , T. Kurokawa , Y. Zhao , K. Sato , A.B. Ihsan , X. Li , H. Guo , J.P. Gong . Adv. Mater. , 2015 . 27 2722 DOI: 10.1002/adma.v27.17 http://doi.org/10.1002/adma.v27.17 .

P. Schaaf , J.B. Schlenoff . Adv. Mater. , 2015 . 27 2420 DOI: 10.1002/adma.201500176 http://doi.org/10.1002/adma.201500176 .

G. Song , L. Zhang , C. He , D.C. Fang , P.G. Whitten , H. Wang . Macromolecules , 2013 . 46 7423 DOI: 10.1021/ma401053c http://doi.org/10.1021/ma401053c .

Y. Sun , G. Gao , G. Du , Y. Cheng , J. Fu . ACS Macro Lett. , 2014 . 3 496 DOI: 10.1021/mz500221j http://doi.org/10.1021/mz500221j .

M. Guo , L.M. Pitet , H.M. Wyss , M. Vos , P.Y.W. Dankers , E.W. Meijer . J. Am. Chem. Soc. , 2014 . 136 6969 DOI: 10.1021/ja500205v http://doi.org/10.1021/ja500205v .

Y. Geng , X.Y. Lin , P. Pan , G. Shan , Y. Bao , Y. Song , Z.L. Wu , Q. Zheng . Polymer , 2016 . 100 60 DOI: 10.1016/j.polymer.2016.08.022 http://doi.org/10.1016/j.polymer.2016.08.022 .

S.Y. Zheng , H. Ding , J. Qian , J. Yin , Y. Song , Z.L. Wu , Q. Zheng . Macromolecules , 2016 . 49 9637 DOI: 10.1021/acs.macromol.6b02150 http://doi.org/10.1021/acs.macromol.6b02150 .

F. Luo , T.L. Sun , T. Nakajima , T. Kurokawa , A.B. Ihsan , X. Li , H. Guo , J.P. Gong . ACS Macro Lett. , 2015 . 4 961 DOI: 10.1021/acsmacrolett.5b00501 http://doi.org/10.1021/acsmacrolett.5b00501 .

F. Zhu , X.Y. Lin , Z.L. Wu , L. Cheng , J. Yin , Y. Song , J. Qian , Q. Zheng . Polymer , 2016 . 95 9 DOI: 10.1016/j.polymer.2016.04.043 http://doi.org/10.1016/j.polymer.2016.04.043 .

F. Zhu , L. Cheng , J. Yin , Z.L. Wu , J. Qian , J. Fu , Q. Zheng . ACS Appl. Mater. Interfaces , 2016 . 8 31304 DOI: 10.1021/acsami.6b09881 http://doi.org/10.1021/acsami.6b09881 .

F. Zhu , L. Cheng , Z.J. Wang , W. Hong , Z.L. Wu , J. Yin , J. Qian , Q. Zheng . ACS Appl. Mater. Interfaces , 2017 . 9 11363 DOI: 10.1021/acsami.7b02007 http://doi.org/10.1021/acsami.7b02007 .

W. Zhao , X. Jin , Y. Cong , Y. Liu , J. Fu . J. Chem. Technol. Biotechnol. , 2013 . 88 327 DOI: 10.1002/jctb.2013.88.issue-3 http://doi.org/10.1002/jctb.2013.88.issue-3 .

A. Nakayama , A. Kakugo , J.P. Gong , Y. Osada , M. Takai , T. Erata , S. Kwano . Adv. Funct. Mater. , 2004 . 14 1124 DOI: 10.1002/(ISSN)1616-3028 http://doi.org/10.1002/(ISSN)1616-3028 .

M. He , Y. Zhao , J. Duan , Z. Wang , Y. Chen , L. Zhang . ACS Appl. Mater. Interfaces , 2014 . 6 1872 DOI: 10.1021/am404855q http://doi.org/10.1021/am404855q .

K. Luo , Y. Yang , Z. Shao . Adv. Funct. Mater. , 2016 . 26 872 DOI: 10.1002/adfm.v26.6 http://doi.org/10.1002/adfm.v26.6 .

R.R. Costa , A.M.S. Costa , S.G. Caridade , J.F. Mano . Chem. Mater. , 2015 . 27 7490 DOI: 10.1021/acs.chemmater.5b03648 http://doi.org/10.1021/acs.chemmater.5b03648 .

M.N. Rodrigues , M.B. Oliveira , R.R. Costa , J.F. Mano . Biomacromolecules , 2016 . 17 2178 DOI: 10.1021/acs.biomac.6b00399 http://doi.org/10.1021/acs.biomac.6b00399 .

J. Fu , H.M. Fares , J.B. Schlenoff . Macromolecules , 2017 . 50 1066 DOI: 10.1021/acs.macromol.6b02445 http://doi.org/10.1021/acs.macromol.6b02445 .

C. Zhang , Q. Ping , Y. Ding , Y. Cheng , J. Shen . J. Appl. Polym. Sci. , 2004 . 91 659 DOI: 10.1002/(ISSN)1097-4628 http://doi.org/10.1002/(ISSN)1097-4628 .

J.M. Silva , N. Georgi , R. Costa , P. Sher , R.L. Reis , C.A. van Blitterswijk , M. Karperien , J.F. Mano . Plos One , 2013 . 8 e55451 DOI: 10.1371/journal.pone.0055451 http://doi.org/10.1371/journal.pone.0055451 .

L. Huang , W. Sui , Y. Wang , Q. Jiao . Carbohyd. Polym. , 2010 . 80 168 DOI: 10.1016/j.carbpol.2009.11.007 http://doi.org/10.1016/j.carbpol.2009.11.007 .

S. Ladet , L. David , A. Domard . Nature , 2008 . 452 76 DOI: 10.1038/nature06619 http://doi.org/10.1038/nature06619 .

M. Kong , X.G. Chen , K. Xing , H.J. Park . Int. J. Food Microbiol. , 2010 . 144 51 DOI: 10.1016/j.ijfoodmicro.2010.09.012 http://doi.org/10.1016/j.ijfoodmicro.2010.09.012 .

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Antimicrobial Properties and Application of Polysaccharides and Their Derivatives

A Self-antibacterial Chitosan-based Polymeric Fluorescent Probe with a Dual-lock Strategy for Ultrafast Detection of Fe3+ in Water System

Thermopower Modulation of Chitosan Hydrogel via Complexation between Chitosan and Metal Ions

Special Topic: Chirality in Polymers

From Molecular Defect to Macroscopic Performance: Manipulating Dichroism and Mechanics in Iodine-doped Poly(vinyl alcohol) via Ethylene Incorporation

Related Author

Gui-Xue Xia

Yue-Ming Wu

Yu-Fang Bi

Kang Chen

Wei-Wei Zhang

Shi-Qi Liu

Wen-Jing Zhang

Run-Hui Liu

Related Institution

Frontiers Science Center for Materiobiology and Dynamic Chemistry, Key Laboratory of Specially Functional Polymeric Materials and Related Technology (ECUST) Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology

Micro-Nano Multiscales Water Science and Green Hydrogen Energy Technology Innovation Research Center, National Engineering Research Center of Water Resources Efficient Utilization and Engineering Safety, Institute of Water Science and Technology, Shool of Renewable Energy, College of Materials Science and Engineering, Hohai University

Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, National Demonstration Center for Experimental Chemistry & Chemical Engineering Education, School of Science, Tianjin University

School of Light Industry Science and Engineering, Beijing Technology and Business University

⁰