Complexation Induced by Weak Interaction between DNA and PEO-<italic style="font-style: italic">b</italic>-P4VP below the CMC of the Polymer

Han Miao; Ya-fen Wang; Hai-yan Dong; Dao-yong Chen

doi:10.1007/s10118-016-1857-6

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Complexation Induced by Weak Interaction between DNA and PEO-b-P4VP below the CMC of the Polymer

PAPERS | Updated：2021-02-18

- Complexation Induced by Weak Interaction between DNA and PEO-b-P4VP below the CMC of the Polymer
- Chinese Journal of Polymer Science Vol. 35, Issue 1, Pages: 46-53(2017)
- Affiliations：
  
  The State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China
- Author bio：
  
  Dao-yong Chen, E-mail:chendy@fudan.edu.cn
- Funds：
- DOI：10.1007/s10118-016-1857-6
  CLC：
- Received：19 May 2016，
  
  Revised：2016-5-25，
  
  Accepted：25 May 2016，
  
  Published：2017-01
- Accepted：
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Han Miao, Ya-fen Wang, Hai-yan Dong, et al. Complexation Induced by Weak Interaction between DNA and PEO-b-P4VP below the CMC of the Polymer[J]. Chinese Journal of Polymer Science, 2017, 35(1): 46-53. DOI: 10.1007/s10118-016-1857-6.
DOI：

Han Miao, Ya-fen Wang, Hai-yan Dong, et al. Complexation Induced by Weak Interaction between DNA and PEO-b-P4VP below the CMC of the Polymer[J]. Chinese Journal of Polymer Science, 2017, 35(1): 46-53. DOI: 10.1007/s10118-016-1857-6. DOI：

摘要

Abstract

The complexation between circular DNA and individual chains of PEO-

-P4VP with a relatively long PEO block and a short P4VP block is highly controllable when the interaction between DNA and the polymer is weak enough. When one circular DNA chain is taken into consideration

and the polymer concentration is far below its critical micelle concentration (CMC)

polymer chains are absorbed by DNA chain due to the interaction between the negatively charged DNA chain and the slightly positively charged P4VP block chains. After the adsorption/complexation

the DNA chain is converted into a nanoring (type 1). In the nanoring

the DNA chain is sufficiently wrapped by the polymer and adopts a fully stretched conformation

so that the DNA compact ratio in the nanorings is close to 1. When the polymer concentration is close to but lower than the CMC

the free polymer chains in the solution are adsorbed not only by the DNA chain but also by the polymer chains that have already been adsorbed on the DNA chain. As a result

the circular DNA chain adsorbs more polymer chains

and thus the resultant nanoring (type 2) has a larger width. In the type 2 nanoring

the DNA chain is slightly compressed; the DNA compact ratio is only about 2-3. Therefore

complexation induced by the weak interaction between DNA and PEO-

-P4VP below the CMC can produce narrow-disperse and large nanorings with a perimeter of micrometers

which are difficult to prepare by existing methods.

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Complexation Induced by Weak Interaction between DNA and PEO-b-P4VP below the CMC of the Polymer

DOI：10.1007/s10118-016-1857-6

摘要

Abstract

关键词

Keywords

references