Tetraphenylethene End-capped Polyethylenimine Fluorescent Nanoparticles for Cell Imaging

Xi-qi Zhang; Xiao-yong Zhang; Bin Yang; Yen Wei

doi:10.1007/s10118-014-1537-3

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Tetraphenylethene End-capped Polyethylenimine Fluorescent Nanoparticles for Cell Imaging

Updated：2021-06-21

- Tetraphenylethene End-capped Polyethylenimine Fluorescent Nanoparticles for Cell Imaging
- Chinese Journal of Polymer Science Vol. 32, Issue 11, Pages: 1479-1488(2014)
- Affiliations：
  
  Department of Chemistry and the Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, China
- Author bio：
  
  **Xi-qi Zhang (张锡奇), E-mail: sychyzhang@126.com
  †These authors contributed equally to this work.
  Yen Wei (危岩), E-mail: weiyen@tsinghua.edu.cn
- Funds：
- DOI：10.1007/s10118-014-1537-3
  CLC：
- Received：03 January 2014，
  
  Revised：2014-05-02，
  
  Accepted：19 June 2014，
  
  Published：2014-11
- Accepted：
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Xi-qi Zhang, Xiao-yong Zhang, Bin Yang, et al. Tetraphenylethene End-capped Polyethylenimine Fluorescent Nanoparticles for Cell Imaging[J]. Chinese Journal of Polymer Science, 2014, 32(11): 1479-1488.
DOI：

Xi-qi Zhang, Xiao-yong Zhang, Bin Yang, et al. Tetraphenylethene End-capped Polyethylenimine Fluorescent Nanoparticles for Cell Imaging[J]. Chinese Journal of Polymer Science, 2014, 32(11): 1479-1488. DOI： 10.1007/s10118-014-1537-3.

摘要

Abstract

Water soluble tetraphenylethene-based (TPE) aggregation-induced emission fluorescent organic nanoparticles (FONs) were facilely prepared

via

Schiff base condensation with polyethylenimine (PEI) and subsequent reduction. The obtained TPE-PEI FONs were characterized by a series of techniques including

H-NMR

C-NMR

gel permeation chromatography

UV absorption spectra

fluorescence spectra

Fourier transform infrared spectroscopy

size distribution and zeta potential measurement

and transmission electron microscopy. Biocompatibility evaluation and cell imaging of TPE-PEI FONs were further explored. We demonstrated that such FONs showed intense fluorescence

spherical morphology and excellent biocompatibility

making them very suitable for cell imaging application.

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