Fabrication of Highly Porous Interconnected Three-dimensional Scaffolds with Micro-channels

Zhi-xiang Cui; Hai-bin Zhao; Yi-yan Peng; Yottha Srithep; Lih-Sheng Turng; Chang-yu Shen

doi:10.1007/s10118-014-1447-4

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Fabrication of Highly Porous Interconnected Three-dimensional Scaffolds with Micro-channels

Updated：2021-06-21

- Fabrication of Highly Porous Interconnected Three-dimensional Scaffolds with Micro-channels
- Chinese Journal of Polymer Science Vol. 32, Issue 7, Pages: 864-870(2014)
- Affiliations：
  
  a.Fujian University of Technology, Fuzhou 350108, China
  b.Shandong University, Jinan 250100, China
  c.University of Wisconsin-Madison, Madison, WI, 53705, USA
  d.Zhengzhou University, Zhengzhou 450002, China
- Author bio：
  
  **Lih-sheng Turng, E-mail: turng@engr.wisc.edu or
  Chang-yu Shen (申长雨), E-mail: shency@zzu.edu.cn
- Funds：
- DOI：10.1007/s10118-014-1447-4
  CLC：
- Received：30 September 2013，
  
  Revised：2013-11-13，
  
  Accepted：14 November 2013，
  
  Published：2014-07
- Accepted：
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Zhi-xiang Cui, Hai-bin Zhao, Yi-yan Peng, et al. Fabrication of Highly Porous Interconnected Three-dimensional Scaffolds with Micro-channels[J]. Chinese Journal of Polymer Science, 2014, 32(7): 864-870.
DOI：

Zhi-xiang Cui, Hai-bin Zhao, Yi-yan Peng, et al. Fabrication of Highly Porous Interconnected Three-dimensional Scaffolds with Micro-channels[J]. Chinese Journal of Polymer Science, 2014, 32(7): 864-870. DOI： 10.1007/s10118-014-1447-4.

摘要

Abstract

A novel highly porous 3-D poly(ε-caprolactone) (PCL) scaffold with micro-channels was fabricated by injection molding and diluent acetic acids leaching technologies. In this study

the chitosan fiber was employed to form the microchannel in PCL matrix. The morphology

porosity and mechanical properties of the scaffolds were studied and calculated. It was found that the larger the content of chitosan fiber is

the higher the porosity would be

due to the volumetric expansion of chitosan fiber in PCL matrix during it being leached. In addition

the less the content of chitosan fiber is

the higher the compressive modulus would be.

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