BIOPOLYMER BASED NANO-DELIVERY SYSTEMS FOR ENHANCING BIOAVAILABILITY OF NUTRACEUTICALS

Bing Hu; Qing-rong Huang

doi:10.1007/s10118-013-1331-7

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BIOPOLYMER BASED NANO-DELIVERY SYSTEMS FOR ENHANCING BIOAVAILABILITY OF NUTRACEUTICALS

Special Issue: In Memory of Prof. Bingzheng Jiang | Updated：2023-01-03

- BIOPOLYMER BASED NANO-DELIVERY SYSTEMS FOR ENHANCING BIOAVAILABILITY OF NUTRACEUTICALS
- Chinese Journal of Polymer Science Vol. 31, Issue 9, Pages: 1190-1203(2013)
- Affiliations：
  
  a.College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
  b.Department of Food Science, Rutgers University, New Brunswick, New Jersey 08901, USA
- Author bio：
  
  **Qing-rong Huang (黄庆荣), E-mail: qhuang@aesop.rutgers.edu
- Funds：
- DOI：10.1007/s10118-013-1331-7
  CLC：
- Received：25 March 2013，
  
  Revised：2013-07-04，
  
  Accepted：10 July 2013，
  
  Published：2013-09
- Accepted：
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Bing Hu, Qing-rong Huang. BIOPOLYMER BASED NANO-DELIVERY SYSTEMS FOR ENHANCING BIOAVAILABILITY OF NUTRACEUTICALS[J]. Chinese Journal of Polymer Science, 2013, 31(9): 1190-1203.
DOI：

Bing Hu, Qing-rong Huang. BIOPOLYMER BASED NANO-DELIVERY SYSTEMS FOR ENHANCING BIOAVAILABILITY OF NUTRACEUTICALS[J]. Chinese Journal of Polymer Science, 2013, 31(9): 1190-1203. DOI： 10.1007/s10118-013-1331-7.

摘要

Abstract

Recently

there has been an increasing interest in the development of efficient food-grade oral nano-delivery systems for encapsulation

protection and target delivery of nutraceuticals to enhance their bioavailability

further to prevent disease and promote human health and well-being. Food proteins represent promising candidates for efficient nutraceutical nanocarriers due to their exceptional characteristics

namely biodegradability

nonantigenicity

high nutritional value

abundant renewable sources and extraordinary binding capacity to various nutraceuticals. In addition

their biocompatibility

biodegradability

low toxicity

low cost

and non-starch polysaccharides possess many favourable characteristics such as stability in the harsh gastric environment

resistance to digestive enzymes

and mucoadhesiveness to intestinal mucosal surface. This review describes the design and formation of nanoscaled delivery systems for nutraceuticals using food-grade proteins (including peptides)

polysaccharides and their associative complexes. The toxicity and cellular uptake fate of the nanostructures

as well as their effects on the intestinal absorption of the encapsulated nutraceuticals were also discussed.

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