A NOVEL ZWITTERIONIC SILANE COUPLING AGENT FOR NONTHROMBOGENIC BIOMATERIALS

Yong-zhi Qiu; Dou-yong Min; Chi Ben; Jian Shen; Qiang Chen; Si-cong Lin

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A NOVEL ZWITTERIONIC SILANE COUPLING AGENT FOR NONTHROMBOGENIC BIOMATERIALS

Papers | Updated：2021-06-21

- A NOVEL ZWITTERIONIC SILANE COUPLING AGENT FOR NONTHROMBOGENIC BIOMATERIALS
- Vol. 23, Issue 6, Pages: 611-617(2005)
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- Published：20 November 2005
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Yong-zhi Qiu, Dou-yong Min, Chi Ben, et al. A NOVEL ZWITTERIONIC SILANE COUPLING AGENT FOR NONTHROMBOGENIC BIOMATERIALS[J]. 2005, 23(6): 611-617.
DOI：

Yong-zhi Qiu, Dou-yong Min, Chi Ben, et al. A NOVEL ZWITTERIONIC SILANE COUPLING AGENT FOR NONTHROMBOGENIC BIOMATERIALS[J]. 2005, 23(6): 611-617. DOI：

摘要

A novel silane coupling agent bearing sulfobetaine group

N-diethyl-N-(3-sulfopropyl)-aminopropyl- trimethoxysilane (DESATS)

was first designed

synthesized and characterized. Its solution property was studied by means of dynamic light scattering. DESATS was successfully bonded onto the surface of the glass and proved by ESCA. Platelet adhesion assay in vitro indicated that the nonthrombogenicity of glass slide modified with DESATS is greatly improved.

Abstract

A novel silane coupling agent bearing sulfobetaine group

N-diethyl-N-(3-sulfopropyl)-aminopropyl- trimethoxysilane (DESATS)

was first designed

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