The aqueous polymerization of acrylamide and crosslinking with N
N-methylenebisacrylamide afforded hydrogelsdisplaying high levels of light scattering (poor optical clarity). Enhancement of the optical clarity within a polyacrylamide(PAm) hydrogel was accomplished through the implementation of "refractive index matching". Water-soluble additives wereutilised to better match the refractive index inhomogeneities throughout a given hydrogel. This resulted in lower light scattering within the system and hence improved clarity.Amino acids
sugars
polymers
and other water-soluble additives such as glycerol were investigated by this methodology.Most addditives investigated displayed potential for effectively reducing the light scattering within a PAm hydrogel as a function of increased additive concentration.On increasing the refractive index of the water medium
the overall refractive index of a PAm hydrogel was also observed to increase.This provided a quantitative means of determining the effectiveness of a given additive for improving the optical clarity within a hydrogel.
Abstract
The aqueous polymerization of acrylamide and crosslinking with N
N-methylenebisacrylamide afforded hydrogelsdisplaying high levels of light scattering (poor optical clarity). Enhancement of the optical clarity within a polyacrylamide(PAm) hydrogel was accomplished through the implementation of "refractive index matching". Water-soluble additives wereutilised to better match the refractive index inhomogeneities throughout a given hydrogel. This resulted in lower light scattering within the system and hence improved clarity.Amino acids
sugars
polymers
and other water-soluble additives such as glycerol were investigated by this methodology.Most addditives investigated displayed potential for effectively reducing the light scattering within a PAm hydrogel as a function of increased additive concentration.On increasing the refractive index of the water medium
the overall refractive index of a PAm hydrogel was also observed to increase.This provided a quantitative means of determining the effectiveness of a given additive for improving the optical clarity within a hydrogel.
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