GRAFTING OF SULFOBETAINE ONTO A POLYURETHANE SURFACE TO IMPROVE BLOOD COMPATIBILITY*

Your Location：

Home >

Browse articles >

GRAFTING OF SULFOBETAINE ONTO A POLYURETHANE SURFACE TO IMPROVE BLOOD COMPATIBILITY*

Papers | Updated：2021-06-21

- GRAFTING OF SULFOBETAINE ONTO A POLYURETHANE SURFACE TO IMPROVE BLOOD COMPATIBILITY*
- Vol. 21, Issue 4, Pages: 419-425(2003)
- Affiliations：
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：20 August 2003
- Accepted：
Scan QR Code
GRAFTING OF SULFOBETAINE ONTO A POLYURETHANE SURFACE TO IMPROVE BLOOD COMPATIBILITY*[J]. 2003, 21(4): 419-425.
DOI：

GRAFTING OF SULFOBETAINE ONTO A POLYURETHANE SURFACE TO IMPROVE BLOOD COMPATIBILITY*[J]. 2003, 21(4): 419-425. DOI：

摘要

On the molecular level

it is believed that polymers containing zwitterionic structures should be compatible withblood. In this work polyurethane films were grafted with sulfobetaine by a three-step procedure. In the first step

the films'surfaces were treated with hexamethylene diisocyanate (HDI) in toluene at 50℃ in the presence of di-n-butyl tin dilaurate(DBTDL) as a catalyst. The extent of the reaction was monitored by ATR-IR spectra; a maximum number of free NCO groups was obtained after a reaction time of 90 min.In the second step

the hydroxyl groups of N

N-dimethylethanolamine(DMEA) were allowed to react in toluene with NCO groups bound on the surface.In the third step

sulfobetaines were formed on the surface through the ring-opening reaction between tertiary amine of DMEA and 1

3-propanesultone(PS).The surfaces of the films were characterized by ATR-IR and XPS showing that the grafted surfaces were composed of sulfobetaine.The results of the contact angle measurement show that the surface was strongly hydrophilic.The platelet adhesion test demonstrated that the films grafted with sulfobetaine have excellent blood compatibility.

Abstract

On the molecular level

the hydroxyl groups of N

N-dimethylethanolamine(DMEA) were allowed to react in toluene with NCO groups bound on the surface.In the third step

sulfobetaines were formed on the surface through the ring-opening reaction between tertiary amine of DMEA and 1

关键词

Keywords

references

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Bioinspired Zinc-doped Nano Hydroxyapatite Reinforced Poly(lactic acid) Composites for Bone Repair

Optically Active Helical Poly(phenyl isocyanide)s Bearing Achiral Benzanilide Pendants: from Controlled Synthesis to Enantioseparation Application

pH-Responsive L-Cysteine-conjugated Polydopamine Nanocarriers for Controlled Release of Emamectin Benzoate against Pieris brassicae

Porous Organic Polymers for Photocatalytic Hydrogen Peroxide Production: Recent Advances and Future Perspectives

Multiple-Responsive Chiral Hydrogels from Helical Dendronized Poly(phenylacetylene)s

Related Author

No data

Related Institution

No data

⁰