SYNTHETIC STUDIES ON BLOOD COMPATIBLE BIOMATERIALS 13:A NOVEL SEGMENTED POLYURETHANE CONTAINING PHOSPHORYLCHOLINE STRUCTURE:SYNTHESIS,CHARACTERIZATION AND BLOOD COMPATIBILITY EVALUATION*

Your Location：

Home >

Browse articles >

SYNTHETIC STUDIES ON BLOOD COMPATIBLE BIOMATERIALS 13:A NOVEL SEGMENTED POLYURETHANE CONTAINING PHOSPHORYLCHOLINE STRUCTURE:SYNTHESIS,CHARACTERIZATION AND BLOOD COMPATIBILITY EVALUATION*

Papers | Updated：2021-06-21

- SYNTHETIC STUDIES ON BLOOD COMPATIBLE BIOMATERIALS 13:A NOVEL SEGMENTED POLYURETHANE CONTAINING PHOSPHORYLCHOLINE STRUCTURE:SYNTHESIS,CHARACTERIZATION AND BLOOD COMPATIBILITY EVALUATION*
- Vol. 21, Issue 1, Pages: 45-50(2003)
- Affiliations：
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：20 February 2003
- Accepted：
Scan QR Code
SYNTHETIC STUDIES ON BLOOD COMPATIBLE BIOMATERIALS 13:A NOVEL SEGMENTED POLYURETHANE CONTAINING PHOSPHORYLCHOLINE STRUCTURE:SYNTHESIS,CHARACTERIZATION AND BLOOD COMPATIBILITY EVALUATION*[J]. 2003, 21(1): 45-50.
DOI：

SYNTHETIC STUDIES ON BLOOD COMPATIBLE BIOMATERIALS 13:A NOVEL SEGMENTED POLYURETHANE CONTAINING PHOSPHORYLCHOLINE STRUCTURE:SYNTHESIS,CHARACTERIZATION AND BLOOD COMPATIBILITY EVALUATION*[J]. 2003, 21(1): 45-50. DOI：

摘要

A new phosphorylcholine

(6-hydroxy) hexyl-2-(trimethylammonio) ethyl phosphate (HTEP)

was synthesized andcharasterized. Segmented polyurethane (SPU) containing phosphorylcholine structure was synthesized based ondiphenylmethane diisocyanate (MDI)

soft segment polytetramethylene glycol (PTMG) and HTEP

with 1

4-butanediol (BD)as a chain extender. The existence of phosphorylcholine structure on the surface of SPU was revealed by attenuated totalreflectance Fourier transform infrard spectroscopy(ATR-FTIR)

X-ray photoelectron spectroscopy(XPS) and water contact angle measurements.The blood compatibilities of the polymers were evaluated by hemolytic testing and a platelet-rich plasma(PRP) adhesion experiment

which was viewed by scanning electron microscopy (SEM) with polyurethane as a reference.The novel segmented polyurethane containing phosphorylcholine structure showed improved blood compatibility.

Abstract

A new phosphorylcholine

(6-hydroxy) hexyl-2-(trimethylammonio) ethyl phosphate (HTEP)

was synthesized andcharasterized. Segmented polyurethane (SPU) containing phosphorylcholine structure was synthesized based ondiphenylmethane diisocyanate (MDI)

soft segment polytetramethylene glycol (PTMG) and HTEP

with 1

4-butanediol (BD)as a chain extender. The existence of phosphorylcholine structure on the surface of SPU was revealed by attenuated totalreflectance Fourier transform infrard spectroscopy(ATR-FTIR)

which was viewed by scanning electron microscopy (SEM) with polyurethane as a reference.The novel segmented polyurethane containing phosphorylcholine structure showed improved blood compatibility.

关键词

Keywords

references

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Sliding Dynamics of Ring Chain on a Rod-Coil Block Copolymer in Rotaxane

Squaramide-directed Cooperative One-dimensional Assembly in Telechelic Polydimethylsiloxane for Hierarchical Network Formation

Pyrimidoisoindigo-based Polymers for Ambipolar Charge Transport

Manipulating Hierarchical Aggregation Structure via Film-forming Kinetics Enables Organic Photovoltaics over 20% Efficiency

One-handed Helical Poly(m-terphenyl acetylene)s with Broad Optical Activity Range from Ultraviolet-Visible to Near-infrared Regions

Related Author

No data

Related Institution

No data

⁰