Emergence of Helical Assemblies in Binary Solvents <italic style="font-style: italic">via</italic> Grafting-from Polymerization-induced Self-assembly of Nanoparticles

Yuqi Guo; Minhui Gao; Lijun Ma; Fenzhao Liu; Hong Liu; Yingxiang Li

doi:10.1007/s10118-026-3883-3

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Emergence of Helical Assemblies in Binary Solvents via Grafting-from Polymerization-induced Self-assembly of Nanoparticles

RESEARCH ARTICLE | Updated：2026-10-30

- Emergence of Helical Assemblies in Binary Solvents via Grafting-from Polymerization-induced Self-assembly of Nanoparticles
- Chinese Journal of Polymer Science Vol. 44, Pages: 1-11(2026)
- Affiliations：
  
  a.Department of Chemical and Material Engineering, Lyuliang University, Lvliang 033001, China
  b.Key Laboratory of Theoretical Chemistry of Environment Ministry of Education, School of Environment, South China Normal University, Guangzhou 510006, China
  c.School of Chemistry, South China Normal University, Guangzhou 510006, China
- Author bio：
  
  hongliu@m.scnu.edu.cn (H.L.)
  yingxiangli@m.scnu.edu.cn (Y.L.)
- Funds：
- DOI：10.1007/s10118-026-3883-3
  CLC：
- Received：02 August 2026，
  
  Accepted：09 September 2026，
  
  Online First：30 October 2026，
  
  Published：2026-10
- Accepted：
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Guo, Y.; Gao, M.; Ma, L.; Liu, F.; Liu, H.; Li, Y. Emergence of helical assemblies in binary solvents via grafting-from polymerization-induced self-assembly of nanoparticles. Chinese J. Polym. Sci. https://doi.org/10.1007/s10118-026-3883-3

Yuqi Guo, Minhui Gao, Lijun Ma, et al. Emergence of Helical Assemblies in Binary Solvents via Grafting-from Polymerization-induced Self-assembly of Nanoparticles[J/OL]. Chinese Journal of Polymer Science, 2026, 441-11. DOI: 10.1007/s10118-026-3883-3.
Guo, Y.; Gao, M.; Ma, L.; Liu, F.; Liu, H.; Li, Y. Emergence of helical assemblies in binary solvents via grafting-from polymerization-induced self-assembly of nanoparticles. Chinese J. Polym. Sci. https://doi.org/10.1007/s10118-026-3883-3 DOI：

Yuqi Guo, Minhui Gao, Lijun Ma, et al. Emergence of Helical Assemblies in Binary Solvents via Grafting-from Polymerization-induced Self-assembly of Nanoparticles[J/OL]. Chinese Journal of Polymer Science, 2026, 441-11. DOI: 10.1007/s10118-026-3883-3. DOI：

摘要

Abstract

Compared with micelles and vesicles formed by the aggregation of conventional polymer chains

the aggregates of grafted nanoparticles demonstrate superior performance in structural stability

functional diversity

and application adaptability. These characteristics indicate their greater potential in fields such as drug delivery

biomateri

als

and intelligent responsive systems. To further expand the range of achievable morphologies

this study introduces co-solvent effects into polymer-grafted nanoparticle systems assembled

via

polymerization-induced self-assembly (PISA). A nanoparticle model featuring dual symmetric initiation sites was developed

and dissipative particle dynamics (DPD) simulations were combined with a stochastic polymerization reaction to systematically investigate the influence of co-solvent interaction strength

nanoparticle filling ratio

and hydrophobic chain length on the self-assembly behavior of grafted nanoparticles. The results reveal that

by precisely tuning the simulation parameters

the controlled formation of various morphologies can be achieved

ranging from conventional spherical and lamellar structures to highly ordered helical aggregates which are preferentially formed when both solvents are strongly solvophobic toward the grafted chains

while a slight asymmetry exists between the two solvent–chain interaction strengths. These findings offer new theoretical insights and methodological support for the morphological control and functional design of polymer-based nanocomposites.

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Emergence of Helical Assemblies in Binary Solvents via Grafting-from Polymerization-induced Self-assembly of Nanoparticles

DOI：10.1007/s10118-026-3883-3

摘要

Abstract

关键词

Keywords

references