Injectable Polymeric Hemostats for Non-compressible Hemorrhage Control

Zheng Pan; Gang He; De-Cheng Wu; Chong Zhang

doi:10.1007/s10118-026-3794-3

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Injectable Polymeric Hemostats for Non-compressible Hemorrhage Control

REVIEW | Updated：2026-09-16

- Injectable Polymeric Hemostats for Non-compressible Hemorrhage Control
- Chinese Journal of Polymer Science Vol. 44, Pages: 1-24(2026)
- Affiliations：
  
  Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen 518055, China
- Author bio：
  
  wudc@sustech.edu.cn (D.C.W.)
  zhangc9@sustech.edu.cn (C.Z.)
- Funds：
- DOI：10.1007/s10118-026-3794-3
  CLC：
- Received：25 May 2026，
  
  Accepted：23 June 2026，
  
  Online First：16 September 2026，
  
  Published：2026-08
- Accepted：
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Pan, Z.; He, G.; Wu, D. C.; Zhang C. Injectable polymeric hemostats for non-compressible hemorrhage control. Chinese J. Polym. Sci. https://doi.org/10.1007/s10118-026-3794-3

Zheng Pan, Gang He, De-Cheng Wu, et al. Injectable Polymeric Hemostats for Non-compressible Hemorrhage Control[J/OL]. Chinese Journal of Polymer Science, 2026, 441-24.
Pan, Z.; He, G.; Wu, D. C.; Zhang C. Injectable polymeric hemostats for non-compressible hemorrhage control. Chinese J. Polym. Sci. https://doi.org/10.1007/s10118-026-3794-3 DOI：

Zheng Pan, Gang He, De-Cheng Wu, et al. Injectable Polymeric Hemostats for Non-compressible Hemorrhage Control[J/OL]. Chinese Journal of Polymer Science, 2026, 441-24. DOI： 10.1007/s10118-026-3794-3.

摘要

Abstract

Non-compressible hemorrhage arising from torso

junctional

or intracavitary injuries remains a major cause of preventable trauma-related mortality owing to anatomically difficult-to-access bleeding sites

rapid high-pressure blood flow

and the limitations of conventional hemostatic approaches. Injectable polymeric hemostats enable minimally invasive delivery into narrow or irregular wound tracts and conformal adaptation to complex wound geometries

representing a promising strategy for effective hemorrhage control. This review summarizes the recent advances in three classes of injectable polymeric hemostats

including hydrogels

gelable powders

and expandable hemostatic materials

with particular emphasis on material design strategies

hemostatic mechanisms

and performance characteristics. Current challenges and future perspectives are also discussed

providing insights to guide the rational design and clinical translation of advanced polymeric hemostats for safer and more effective management of non-compressible hemorrhage.

关键词

Keywords

references

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