pH-Responsive L-Cysteine-conjugated Polydopamine Nanocarriers for Controlled Release of Emamectin Benzoate against <italic style="font-style: italic">Pieris brassicae</italic>

Kirna Devi; Sunil Kumar; Ishani Saini; Alka Rana; Rajender Kumar

doi:10.1007/s10118-026-3699-1

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pH-Responsive L-Cysteine-conjugated Polydopamine Nanocarriers for Controlled Release of Emamectin Benzoate against Pieris brassicae

RESEARCH ARTICLE | Updated：2026-08-31

- pH-Responsive L-Cysteine-conjugated Polydopamine Nanocarriers for Controlled Release of Emamectin Benzoate against Pieris brassicae
- Chinese Journal of Polymer Science Vol. 44, Issue 9, Pages: 3026-3041(2026)
- Affiliations：
  
  a.Department of Chemistry and Chemical Sciences, School of Physical and Material Sciences, Central University of Himachal Pradesh, Dharamshala-176215, Himachal Pradesh, India
  b.Department of Animal Sciences, School of Life Sciences, Central University of Himachal Pradesh, Dharamshala-176215, Himachal Pradesh, India
- Author bio：
  
  rajender.cuhp@gmail.com
- Funds：
- DOI：10.1007/s10118-026-3699-1
  CLC：
- Received：02 February 2026，
  
  Accepted：04 April 2026，
  
  Online First：03 August 2026，
  
  Published：05 September 2026
- Accepted：
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Devi, K.; Kumar, S.; Saini, I.; Rana, A.; Kumar, R. pH-Responsive L-cysteine-conjugated polydopamine nanocarriers for controlled release of emamectin benzoate against pieris brassicae. Chinese J. Polym. Sci. 2026, 44, 3026–3041

Kirna Devi, Sunil Kumar, Ishani Saini, et al. pH-Responsive L-Cysteine-conjugated Polydopamine Nanocarriers for Controlled Release of Emamectin Benzoate against Pieris brassicae[J]. Chinese Journal of Polymer Science, 2026, 44(9): 3026-3041. DOI: 10.1007/s10118-026-3699-1.
Devi, K.; Kumar, S.; Saini, I.; Rana, A.; Kumar, R. pH-Responsive L-cysteine-conjugated polydopamine nanocarriers for controlled release of emamectin benzoate against pieris brassicae. Chinese J. Polym. Sci. 2026, 44, 3026–3041 DOI： 10.1007/s10118-026-3699-1.

Kirna Devi, Sunil Kumar, Ishani Saini, et al. pH-Responsive L-Cysteine-conjugated Polydopamine Nanocarriers for Controlled Release of Emamectin Benzoate against Pieris brassicae[J]. Chinese Journal of Polymer Science, 2026, 44(9): 3026-3041. DOI: 10.1007/s10118-026-3699-1. DOI：

摘要

A green-synthesized L-cysteine-conjugated Polydopamine (PDC) nanocarriers was developed for efficient encapsulation and controlled release of emamectin benzoate (EMB). The nanocarriers exhibits pH-responsive release behavior

enhanced photostability

adhesion and insecticidal efficacy

offering a sustainable strategy in smart pesticide delivery system.

Abstract

Biodegradable polymeric nanocarriers demonstrate significant potential for the controlled release of pesticides

offering a sustainable and efficient approach for agriculture. This study involves the synthesis of novel pH-responsive L-cysteine-conjugated polydopamine (PDC) nanospheres for the controlled release of emamectin benzoate (EMB). Using sustainable

in situ

polymerization

hydrophobic EMB was encapsulated within biodegradable polydopamine (PDA)

which was further conjugated with L-cysteine. The functionalized and encapsulated carriers were characterized using UV

visible spectroscopy

Fourier-transform infrared spectroscopy (FTIR)

thermogravimetric analysis (TGA)

zeta potential

field emission scanning electron microscopy (FE-SEM)

high-resolution transmission electron microscopy (HR-TEM)

and X-ray photoelectron spe

ctroscopy (XPS). Both EMB@PDA and EMB@PDC nanospheres were assessed for their encapsulation efficiency and pH-responsive release of EMB. Under varying pH and temperature conditions

the maximum cumulative release of EMB was achieved at pH=3 and was further enhanced by temperature. Various kinetic models have shown that Fick’s diffusion controls the release process. EMB@PDC nanospheres exhibited excellent adhesion to plant surfaces and effectively protected against UV radiation

which reduced EMB loss through rainfall washout and photolytic degradation. In addition

EMB@PDC exhibited high insecticidal potency against

Pieris brassicae

. Hence

this integrative platform exemplifies an effective pesticide delivery system for promoting agricultural sustainability.

关键词

Keywords

references

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⁰

pH-Responsive L-Cysteine-conjugated Polydopamine Nanocarriers for Controlled Release of Emamectin Benzoate against Pieris brassicae

DOI：10.1007/s10118-026-3699-1

摘要

Abstract

关键词

Keywords

references