Perforation Dynamics and Directional Motion of Janus Vesicles under the Coupled Effects of Flow and Electric Fields

Yi-Ning Zhang; Yun-Long Han; Jia-Wei Li; Tong-Fei Shi

doi:10.1007/s10118-025-3430-7

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Perforation Dynamics and Directional Motion of Janus Vesicles under the Coupled Effects of Flow and Electric Fields

RAPID COMMUNICATION | Updated：2025-10-30

- Perforation Dynamics and Directional Motion of Janus Vesicles under the Coupled Effects of Flow and Electric Fields
- Chinese Journal of Polymer Science Vol. 43, Issue 11, Pages: 1939-1949(2025)
- Affiliations：
  
  a.School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, China
  b.School of Mechanical Engineering, Dalian University of Technology, Dalian 116024, China
  c.Department of Mathematics and Statistics, Boston University, 665 Commonwealth Avenue, Boston, Massachusetts 02215, USA
- Author bio：
  
  yunlonghan@mail.dlut.edu.cn (Y.L.H.)
  tfshi@gdut.edu.cn (T.F.S.)
- Funds：
- DOI：10.1007/s10118-025-3430-7
  CLC：
- Received：30 June 2025，
  
  Accepted：08 August 2025，
  
  Online First：16 October 2025，
  
  Published：05 November 2025
- Accepted：
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Zhang, Y. N.; Han, Y. L.; Li, J. W.; Shi, T. F. Perforation dynamics and directional motion of janus vesicles under the coupled effects of flow and electric fields. Chinese J. Polym. Sci. 2025, 43, 1939–1949

Yi-Ning Zhang, Yun-Long Han, Jia-Wei Li, et al. Perforation Dynamics and Directional Motion of Janus Vesicles under the Coupled Effects of Flow and Electric Fields[J]. Chinese Journal of Polymer Science, 2025, 43(11): 1939-1949.
Zhang, Y. N.; Han, Y. L.; Li, J. W.; Shi, T. F. Perforation dynamics and directional motion of janus vesicles under the coupled effects of flow and electric fields. Chinese J. Polym. Sci. 2025, 43, 1939–1949 DOI： 10.1007/s10118-025-3430-7.

Yi-Ning Zhang, Yun-Long Han, Jia-Wei Li, et al. Perforation Dynamics and Directional Motion of Janus Vesicles under the Coupled Effects of Flow and Electric Fields[J]. Chinese Journal of Polymer Science, 2025, 43(11): 1939-1949. DOI： 10.1007/s10118-025-3430-7.

摘要

This work reveals the perforation dynamics and directional motion of Janus vesicles under coupled flow–electric fields. Flow governs propulsion and shear

while field strength and membrane charge distribution regulate migration and deformation. Adjusting field orientation enables precise post-perforation guidance for targeted microfluidic applications.

Abstract

Janus vesicles

unique nanostructures

have attracted significant attention for their diverse applications in biomedical and microfluidic systems. In practical micro-nano systems

flow and electric fields often coexist

and the perforation dynamics of Janus vesicles exhibit complex motion due to their synergistic effects. Studying Janus vesicle perforation dynamics under the combined influence of fluid flow and electric fields provides valuable insights into their applications in drug delivery

catalyst delivery

and controlled release. This study focuses on the perforation dynamics and directional motion of Janus vesicles in microchannels

emphasizing how electric field strength and charge distribution on the membrane influence vesicle migration

deformation

and trajectories. Results show that when electromagnetic forces and flow-driven forces align

increasing electric field strength promotes vesicle migration and perforation. Vesicle migration is correlated with charge distribution on the membrane

with broader distributions resulting in more pronounced migration. When electric field strength remains constant

charge distribution has little effect on vesicle deformation. Conversely

when electromagnetic forces and flow-driven forces oppose

increasing electric field strength inhibits vesicle migration. At a specific potential difference

charged vesicles cease movement before reaching the perforation site

indicating the critical potential for perforation. The study also reveals that the direction of the electric field significantly affects vesicle migration direction. Adjusting potential values at microchannel boundaries can control the directional movement of Janus vesicles. This research provides new insights into Janus vesicle behavior in complex environments and deepens understanding of their potential as drug carriers for delivery and targeted therapy.

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references

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Related Institution

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