FOLLOWUS
a.School of Mechanical Engineering, Jiangsu University, Zhenjiang 212013, China
b.International Genomics Research Center, Jiangsu University, Zhenjiang 212013, China
1000003037@ujs.edu.cn
Received:30 October 2024,
Revised:15 December 2024,
Accepted:2024-12-17,
Published Online:13 February 2025,
Published:01 March 2025
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Meng, Y. F.; Dong, Y. L.; Na, M. L.; Xu, L. An advanced hydrogel-based facial mask for skin quality testing. Chinese J. Polym. Sci. 2025, 43, 495–508
Yan-Fang Meng, Yu-Liao Dong, Man-Li Na, et al. An Advanced Hydrogel-based Facial Mask for Skin Quality Testing[J]. Chinese journal of polymer science, 2025, 43(3): 495-508.
Meng, Y. F.; Dong, Y. L.; Na, M. L.; Xu, L. An advanced hydrogel-based facial mask for skin quality testing. Chinese J. Polym. Sci. 2025, 43, 495–508 DOI: 10.1007/s10118-025-3287-9.
Yan-Fang Meng, Yu-Liao Dong, Man-Li Na, et al. An Advanced Hydrogel-based Facial Mask for Skin Quality Testing[J]. Chinese journal of polymer science, 2025, 43(3): 495-508. DOI: 10.1007/s10118-025-3287-9.
To make up the gap/deficiency of unavailable of effective methodologies for real-time assessment of skin quality currently in the market
we have developed an innovative non-toxic
light-activated natural material collagen peptide-lithium chloride hydrogel mask
to effectively distinguishing various skin types.
In the event of the ever-increasing growth of the beauty industry and the burgeoning market for facial masks
high-performance and high-safety mask products have emerged. Among these
light-cured collagen peptide-based hydrogels
which are non-toxic
photocurable natural materials
exhibit significant potential for use in facial masks. We developed a novel collagen peptide-lithium chloride hydrogel-based facial mask. Light-cured collagen peptide hydrogel is a non-toxic
light-activated natural material that holds considerable promise for application in facial masks. Nonetheless
there is a significant lack of effective methodologies for real-time assessment of skin quality currently available in the market. To address this deficiency
we have developed an innovative collagen peptide-lithium chloride hydrogel mask
which is characterized by exceptional transparency (98% within the visible spectrum of 400−800 nm)
commendable tensile properties (tensil
e strength of 428.6±2.1 kPa
with a tensile strength increase of 123.9%)
substantial water retention capacity (61%)
and favorable antimicrobial efficacy (89%). The incorporation of lithium chloride enhances ionic conduction at the interface between the human body and hydrogel
thereby enabling quantitative evaluation of skin quality through impedance analysis. Our collagen peptide-lithium chloride hydrogel facial mask demonstrated effectiveness in distinguishing various skin types
including D
+
(severely dry)
D (mildly to moderately dry)
N (moderate)
O (mildly to moderately oily)
and O
+
(severely oily). This study presents significant opportunities for the advancement of hydrogel masks and provides a new application platform for polymer hydrogels.
Waltz, E. Cosmetics: when biotech is better than nature. Nat. Biotechnol. 2022 , 40 , 626−628..
Bowman, D. M.; van Calster, G.; Friedrichs, S. Nanomaterials and regulation of cosmetics. Nat. Nanotechnol. 2022 , 5 , 92−92..
Xu, X. K.; Guo, L.; Liu, H.; Zhou, Z. X.; Li, S.; Gu, Q. Ding, S. L.; Guo, H. T.; Yan, Y.; Lan, Y. Q.; Li, Q. L.; Wei, W. X.; Zhang, J.; Liu, C.; Su, Y. W. Stretchable electronic facial masks for skin electroporation. Adv. Funct. Mater. 2024 , 34 , 2311144..
Bilgi, E.; Gokce, E. H.; Bayir, E.; Sendemir, A.; Ozer, K. O.; Tuna, E. E. H. Bacterial cellulose based facial mask with Antioxidant property and high moisturizing capacity. Cellulose 2021 , 28 , 10399−10414..
Wang, R.; Li, J. Z.; Chen, W.; Xu, T. T.; Yun, S. F.; Xu, Z.; Xu, Z. Q.; Sato, T.; Chi, B.; Xu, H. A biomimetic mussel-inspired ε -poly-L-lysine hydrogel with robust tissue-anchor and anti-infection capacity. Adv. Funct. Mater. 2017 , 27 , 1604894..
Wang, J.; Sun, Y. M.; Liu, X. Q.; Kang, Y. Y.; Cao, W. B.; Ye, J.; Gao, C. Y. An antibacterial and anti-oxidant hydrogel containing hyperbranched poly-L-lysine and tea polyphenolsaccelerates healing of infected wound. Biomater. Adv. 2024 , 157 , 213755..
Chen, J. L.; Cai, Z. Y.; Wei, Q. R.; Wang, D.; Wu, J.; Tan, Y. F.; Lua, J.; Ai, H. Proanthocyanidin-crosslinked collagen/konjac glucomannan hydrogel with improved mechanical properties and MRI trackable biodegradation for potential tissue engineering scaffolds. J. Mater. Chem. 2020 , 8 , 316−331.
Du, Y. Z.; Fan, D. D.; Ma, X. X.; Zhu, C. H. Zhang, L. J. Study the biodegradation of an injection human-like collagen hydrogel. Adv. Eng. Mater. 2012 , 535 , 2291−2295..
You, D. G.; Jung, J. M.; Kim, C. H.; An, J. Y.; Bui, V. D.; Lee, J. M.; Um, W.; Jo, D. G.; Cho, Y. W.; Lee, D. S.; Balaj, L.; Lee, H.; Park, J. H. Stem cell-derived extracellular vesicle-bearing injectable hydrogel for collagen generation in dermis. ACS Appl. Mater. Interfaces 2024 , 16 , 37698−37706..
Wang, Q.; Yan, H. Y.; Zhang, J. T.; Tian, X. Y.; Xiao, J. X. Engineering a durable BDDE cross-linked collagen filler for skin rejuvenation. Biomedical. Mater. 2024 , 19 , 055021..
Yang, G. W.; Chen, X. Y.; Shi, W. J.; Chen, N.; Liu, Y.; Zhang, B.; Shao, Z. Z. Facile preparation of a photo-cross-linked silk fibroin-poly ionic liquid hydrogel with anti-freezing and ion conductive properties. ACS Appl. Mater. Interfaces 2024 , 16 , 1543−1552..
Oh, J. J.; Ammu, S.; Vriend, V. D.; Kieffer, R.; Kleiner, F. H.; Balasubramanian, S.; Karana, E.; Masania, K.; Aubin-Tam, M. E. Growth, distribution, and photosynthesis of Chlamydomonas Reinhardtii in 3D hydrogels. Adv. Mater. 2024 , 36 , 2305505..
Zhou, C.; Li, P.; Qi, X.;Sharif, A. R. M.; Poon, Y. F.; Cao, Y.; Chang, M. W.; Leong, S. S. J.; Chan-Park, M. B. A photo-polymerized antimicrobial hydrogel coating derived from ε -poly-L-lysine. Biomaterials 2011 , 32 , 2704−2712..
Meng, Y. W.; Niu, Y. Q.; Ye, C. D.; He, X. F.; Meng, L. F.; Zhang, Z. X.; Hsu, K. C.; Lin, X. R.; Andrew, S.; Zhang, X. H.; Frederic, F.; Wu, Y. Efficacy of a moisturizing cream and Facial mask for alleviating skin problems associated with medical mask use: a half-face, randomized controlled study. J. Cosmet. Dermatol. 2024 , 23 , 2097−2102..
Li, S.; Xu, J. W.; Li, R.; Wang, Y. K.; Zhang, M. Y.; Li, J.; Yin, S. Z.; Liu, G. D.; Zhang, L. J.; Li, B. Q.; Gu, Q. Y.; Su. W. Stretchable electronic facial masks for sonophoresis. ACS Nano 2022 , 16 , 5961−5974..
Xiao, M.; Tan, M.; Peng, C.; Jiang, F.; Wu, K.; Liu, N.; Li, D.; Yao, X. L. Soft and flexible polyvinyl alcohol/pullulan aerogels with fast and high water absorption capacity for facial mask substrates. Int. J. Biol. Macromol. 2024 , 264 , 130469..
Xia, K. Q.; Xu, Z. W. Applying a triboelectric nanogenerator by using facial mask for flexible touch sensor applying a triboelectric nanogenerator by using facial mask for flexible touch sensor. Sens. Actuator. B-Chem. 2021 , 331 , 112710..
Eg awa, M.; Oguri, M.; Hirao, T.; Takahashi, M.; Miyakawa, M. The evaluation of skin friction using a frictional feel analyzer. Skin Res. Technol. 2002 , 8 , 41−51..
Corcuff, P.; Lev´ eque, J. L. Skin surface replica image, in: J. Serup, ˆ G.B.E. Jemec (Eds.), Analysis of Furrows and Wrinkles: Handbook of Non-Invasive Methods and the Skin , CRC Press 1995 , 89−96..
Makki, S.; Mignot, J.; Zahouani, H. Statistical analysis of the skin surface and three dimensional representation of human skin. J. Soc. Cosmet. Chem. 1985 , 35 , 311−317..
Romano, R. A.; Rosa, R. G. T.; Salvio, A. G.; Jo, J. A.; Kurachi, C. Multispectral autofluorescence dermoscope for skin lesion assessment. Photodiagn. Photodyn. Therapy 2020 , 30 , 101704.
Kyritsis, A.; Pissis, P.; Grammatikakis, J. Dielectric relaxation spectroscopy in poly(hydroxyethyl acrylates)/water hydrogels. J. Polym. Sci., Part B: Polym. Phys. 1995 , 33 , 1737−1750..
Zhang, D. B.; Zhang, M. Y.; Wang, J. W.; Sun , H. L.; Liu, H.; Mi, L. W.; Liu, C. T.; Shen, C. Y. Impedance response behavior and mechanism study of Axon-like Ionic conductive cellulose-based hydrogel strain sensor. Adv. Compos. Hybrid. Mater. 2022 , 5 , 1812−1820..
Okutan, M.;Yavuz, E.; Özerol, E. A.; Şenkal, B. F.; Yalçın, O.; Yıldız, A. Impedance spectroscopy of Polyaniline coated hydrogel. Polym. Bull. 2021 , 78 , 4473−4486..
Sosa, M.; Bernal-Alvarado, J.; Jiménez-Moreno, M.; Hernández, J. C.; Gutiérrez-Juárez, G.; Vargas-Luna, M.; Huerta, M.; Villagómez Castro, J. C.; Palomares, P. Magnetic field influence on electrical properties of human Blood measured by impedance spectroscopy. Bioelectromagnetics 2005 , 26 , 564−570..
Burton, C. E.; Burton, W. M.; Akers, L. A. The application of bode analysis to skin impedance. Psychophysiology 1974 , 11 , 517..
Hernández, F.; Salazar, C. A.; Bernal, J. J. Determinación de laspropied ade seléctrica sentejido sanguíneo. Ciencia U. ANL. 2007 , 510 , 51525..
Mech-Dorosz, A.; Khan, M. S.; Mateiu, R. V.; Hélix-Nielsen, C.; Emnéus, J.; Heiskanen, A. Impedance characterization of biocompatible hydrogel suitable for Biomimetic lipid membrane applications. Electrochimica. Acta 2021 , 373 , 137917..
Cai, W.; Xie, S. B.; Zhang, J.; Tang, D.; Tang, Y. An electrochemical impedance biosensor for Hg 2+ detection based on DNA hydrogel by coupling with DNA-enzyme-assisted target recycling and hybridization chain reaction. Biosens. Bioelectron. 2017 , 98 , 466−472..
Turo, F. D.; Matricardi, P.; Meo, C. D.; Mazzei, F.; Favero, G.; Zane, D. PVA hydrogel as polymer electrolyte for electrochemical impedance analysis on archaeological metals. J. Cult. Herit. 2019 , 37 , 113−120..
Chen, H. F.; Yang, X.; Geng, J. L.; Ma, G.; Wang, X. A skin-like hydrogel for distributed force sensing using an electrical impedance tomography-based 29 pseudo-array method. ACS Appl. Electron. Mater. 2023 , 5 , 1451−1460..
Lou, D. Y.; Wang, C. S.; He, Z. Y.; Sun, X. Y.; Luo, J. S.; Li, J. Robust organohydrogel with flexibility and conductivity across the Freezing and Boiling temperatures of water. Chem. Commun. 2019 , 55 , 8422−8425..
Autelitano, F.; Longo, S. Felice Giuliani Phyto-based sodium chloride hydrogel for highway winter maintenance of porous asphalt pavements. Cons. Build. Mater. 2022 , 319 , 126082..
Tanveer, S.; Chen, C. C. Thermodynamic analysis of hydrogel swelling in aqueous sodium chloride solutions. J. Mol. Liq. 2022 , 348 , 118421..
Lia, Y.; Hea, J. T.; Lyua, X. L.; Yuana, Y.; Wang, C. Z.; Zhao, B. H. Chitosan-based thermosensitive hydrogel for nasal delivery of exenatide: effect of magnesium chloride. Inter. J. Pharm. 2018 , 553 , 375−385.
De Mello Innocentini, M. D.; Bueno, B. R. F.; Urbas, A.; Microstructural, A. M. C. Fluid dynamic, and mechanical characterization of zinc oxide and magnesium chloride-modified hydrogel scaffolds. ACS Biomater. Sci. Eng. 2024 , 10 , 4791−4801..
Choi, CW; Choi, J. W.; Youn, S. W. Subjective facial skin type, based on the sebum related symptoms, can reflect the objective casual sebum level in acne patients. Skin Res. Technol. 2012 , 19 , 176−182..
Dawson, J. B.; Barker D. J.; Ellis, D. J. A theoretical and experimental study of light absorption and scattering by in vivo skin. Phys. Med. Biol. 2000 , 25 , 695−709..
Lee, E. S. Satisfaction and management attitude for skin according to age and skin type. Asian J. Beaut. Cosmetol. 2011 , 9 , 1−11..
Nguyen, K. D.; Kobayashi, T. Chitin hydrogels prepared at various lithium chloride/ N,N -dimethylacetamide solutions by water vapor-induced phase inversion. J. Chem. 2020 , 12 , 6645351..
Wen, Z.; Xin, C.; Zhong, S. Infrared and Raman spectroscopy for the study of filament protein conformation. Adv. Chem. 2006 , 18 , 1514−1522..
Sun, T. L.; Kurokawa, T.; Kuroda, S.; Ihsan, A. B.; Akasaki, T.; Sato, K.; Haque, Md. A.; T. Nakajima, T.; Gong, J. P. Physical hydrogels composed of polyampholytes demonstrate high toughness and viscoelasticity. Nat. Mater. 2013 , 12 , 932−937..
Lodge, T P.; Mcleish, T. C. Self-concentrations and effective glass transition temperatures in polymer blends. Macromolecules 2000 , 33 , 5278−5284..
Lipson, J. E.; Milner, S. T. Multiple glass transitions and local composition effects on polymer solvent mixtures. J. Polym. Sci., Part B: Polym. Phys. 2006 , 44 , 3528−3545..
Pek, Y. S.; Wan, A. C. A.; Ying, J. Y. The effect of matrix stiffness on mesenchymal stem cell differentiation in a 3D thixotropic gel. Biomaterials 2010 , 31 , 385−391..
Ehrbar, M.; Sala, A.; Lienemann, P.; Ranga, A.; Mosiewicz, K.; Bittermann, A.; Rizzi, S. C.; Weber, F. E.; Lutolf, M. P. Elucidating the role of matrix stiffness in 3d cell migration and remodeling. Biophys. J. 2011 , 100 , 284−293..
Hamdaoui, L.; Bouchti, M.; Moussaouiti, M. Comparison of rheological pro-perties of kraft and microcrystalline cellulose dissolved in lithium chloride/ N,N -dimethylacetamide. Polym. Bull. 2018 , 75 , 769−779..
Li, L. L.; Wang, X. W.; Gao, S.; Zheng, S. J.; Zou, X. Y.; Xiong, J. F.; Li, W. Z.; Yan, F. High-toughness and high-strength solvent-free linear poly(ionic liquid) elastomers. Adv. Mater. 2024 , 36 , 2308547..
Wang, Y. M.; Huang, F.; Chen, X. B; Wang, X. W.; Zhang, W. B.; Peng, J.; Li, J. Q.; Zhai, M. L. Stretchable, conductive, and self-healing hydrogel with super metal adhesion. Chem. Mater. 2018 , 30 , 4289−4297..
Gu, T. R.; Li, W. L.; Ma, J.; Dai, M.; Cheng, H. M. in Surface Chemistry , Beijing Chemical Industry, 1994 , 15..
Janting, J.; Pedersen, J. K. M.; Woyess, A. G.; Nielsen, K.; Bang, O. Small and robust all-polymer fiber Bragg grating based pH sensor. J- LT . 2019 , 37 , 4480-4486..
Dorf, R. C.; Svoboda, J. A. in Introduction to Electric Circuits , Wiley, 2009 ..
Cahan, B. D.; Wainright, J. S. AC impedance investig ations of proton conduction in Nafion. J. Electrochem. Soc. 1993 , 140 , 185−186..
Hekstra, D. R.; White, K. I.; Socolich, M. A.; Henning, R. W.; Srajer, V.; Ranganathan, R. Electric-field-stimulated protein mechanics. Natrue 2016 , 540 , 400−405..
Moroni, A.; Varde, C.; Giustetto, A.; Stagi, S.; Marini, E.; Cremasco, M. M. Bioelectrical impedance vector analysis (BIVA) for the monitoring of body composition in pregnancy. Eur. J. Clin. Nutr. 2022 , 76 , 604−609..
Rusua, C.; Krozera, A.; Johanssona, C.; Ahrentorpa, F.; Petterssona, T.; Christian Jonassona, C.; Rösevalla, J.; Ilvera, D.; Terzaghib, M.; Chiatanteb, D.; Montagnoli, A. Miniaturized wireless water content and Conductivity soil sensor system. Comput. Electron. Agr. 2019 , 167 , 10507..
Yoshino, T.; Shimojuku A. Li, D. Electrical conductivity of Stishovite as a function of water content. Phys. Earth. Planet. In. 2014 , 227 , 48−54..
Mahdavian, M.; Attar, M. M. Another approach in analysis of paint coatings with EIS meas urement: phase angle at high frequencies. Corros. Sci. 2006 , 48 , 4152−4157..
Touzain, S. Some comments on the use of the EIS phase angle to evaluate organic coating degradation. Electrochim. Acta 2010 , 55 , 6190−6194..
Peng, Z.Y.; Peng, Z. P.; Shen, Y. Q. Study on biological safety of polyvinyl alcohol/collagen hydrogel as a tissue substitute (II). JMS-PAC. 2011 , 48 , 632−636..
Firooz, A.; Sadr, B.; Babakoohi, S. Variation of biophysical parameters of the skin with age, gender, and body region. Sci. World J. 2012 , 6 , 386936..
Kikuchi, K; Kobayashi, H; Le, F. The winter season affects more severely the facial skin than the forearm skin: comparative biophysical studies conducted in the same japanese females in later summer and winter. Exogenous Dermatology 2002 , 1 , 32−38..
Lee, J. H.; Heo, S.; Kim, Y. J.; Eom, J.; H. J. Jung, H. Kim, J. W.; Kim, I.; Park, H. H.; Mo, H. S.; Kim, Y. H.; Park, S. K. A behavior-learned cross-rea ctive sensor matrix for intelligent skin perception. Adv. Mater. 2020 , 32 , 2000969..
Polat, B.; Polat, L. L.; Hsu, P. Y.; Kaipu, V.; Mercier, P. P.; Cheng, C. K.; Lipomi, D. J. ACS Appl. Nano Mater . 2021 , 4, 8126..
Jiang, Y.; Sadeqi, A.; Miller, E. L.; Sonkusale, S. Head motion classification using thread-based sensor and machine learning algorithm. Sci. Rep. 2021 , 11 , 2646..
Shin, H.; Oh, S.; Hong, S.; Kang, M.; Kang, D.; Ji, Y.; Choi, B. H.; Kang, K.; Jeong, H.; Park, Y.; Hong, S.; Kim, H. K.; Choi, Y. Early-stage lung cancer diagnosis by deep learning-based spectroscopic analysis of circulating exosomes. ACS Nano 2020 , 14 , 5435−5444..
Swift, A.; Liew, S.; Weinkle S.; Garcia, J. K.; Silberberg, M. B. The facial aging process from the "inside out" (OUP). Aesthet. Surg. J. 2021 , 41 , 1107−1119..
Cho, C.; Lee, E.; Park, G.; Cho, E.; Kim, N.; Shin, J.; Woo, S.; Ha, J.; Hwang, J. Evaluation of f acial skin age based on biophysical properties in vivo. J. Cosmet. Dermatal . 2022 , 21 , 3546-3554..
Flament, F.; Prunel, A.; Keufer, B. Changes in Facial signs due to age and their respective weights on the perception of age and skin plumpness among different aged Koreaan women. Skin Res. Technol. 2021 , 4 , 526−536.
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