Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection

Jiao He; Hua-Jian Song; Zuo-An Liu; Bing-Li Jiang; Yong-Yang Gong; Wang-Zhang Yuan

doi:10.1007/s10118-024-3161-1

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Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection

RESEARCH ARTICLE | Updated：2024-11-04

- Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection
- Chinese Journal of Polymer Science Vol. 42, Issue 11, Pages: 1679-1689(2024)
- Affiliations：
  
  a.Guangxi Key Laboratory of Optical and Electronic Materials and Devices, College of Materials Science and Engineering, Guilin University of Technology, Guilin 541004, China
  b.College of Pharmacy, Guilin Medical University, Guilin 541199, China
  c.School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
- Author bio：
  
  yygong@glut.edu.cn (Y.Y.G.)
  wzhyuan@sjtu.edu.cn (W.Z.Y.)
- Funds：
- DOI：10.1007/s10118-024-3161-1
  CLC：
- Received：08 March 2024，
  
  Revised：2024-04-27，
  
  Accepted：12 May 2024，
  
  Online First：20 August 2024，
  
  Published：30 November 2024
- Accepted：
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He, J.; Song, H. J.; Liu, Z. A.; Jiang, B. L.; Gong, Y. Y.; Yuan, W. Z. Efficient and pH-sensitive nonconventional luminescent polymers for cellular imaging and ion detection. Chinese J. Polym. Sci. 2024, 42, 1679–1689

Jiao He, Hua-Jian Song, Zuo-An Liu, et al. Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection[J]. Chinese Journal of Polymer Science, 2024, 42(11): 1679-1689.
He, J.; Song, H. J.; Liu, Z. A.; Jiang, B. L.; Gong, Y. Y.; Yuan, W. Z. Efficient and pH-sensitive nonconventional luminescent polymers for cellular imaging and ion detection. Chinese J. Polym. Sci. 2024, 42, 1679–1689 DOI： 10.1007/s10118-024-3161-1.

Jiao He, Hua-Jian Song, Zuo-An Liu, et al. Efficient and pH-Sensitive Nonconventional Luminescent Polymers for Cellular Imaging and Ion Detection[J]. Chinese Journal of Polymer Science, 2024, 42(11): 1679-1689. DOI： 10.1007/s10118-024-3161-1.

摘要

Nonconventional luminescent polymers exhibit remarkably high luminescence efficiency

reaching up to 9.2% in dilute solutions (0.1 mg/mL)

and their optical properties are highly responsive to a range of variables

including pH

excitation wavelength

concentration

temperature and metal ions. Due to these unique optical properties and their good biocompatibility

these materials have emerged as a promising class of materials for cell imaging applications.

Abstract

Nonconventional luminescent materials (NLMs) are a type of organic luminescent materials that does not contain aromatic units. Due to the simplicity of the synthesis process

mild reaction conditions

good hydrophilicity and biological compatibility

NLMs have attracted much attention. Nevertheless

numerous reports indicate that NLMs can only effectively luminesce at high concentrations and in solid state

which limits their applicability in the field of cell imaging. This study addresses this limitation by designing and synthesizing oligomers P1

P2 and P3 using ethylene glycol diglycidyl ether and amine compounds containing ethylene groups. These oligomers exhibit remarkable luminescence efficiency reaching as high as 9.2% in dilute solutions (0.1 mg/mL)

making them among the best NLMs in this category. Furthermore

the synthesized oligomers exhibit excitation wavelength-dependent and concentration-dependent luminescence intensity

fluorescence response to temperature and pH changes

as well as the ability to identify Fe

and Mo

in dilute solutions. These characteristics render them potentially useful in the for cell imaging.

关键词

Keywords

references

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